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Comparing QCM & MP-SPR: A flowrate study

Application Note #129

AN#129 Comparing QCM & MP-SPR. A flowrate study

Liposomes interaction with streptavidin functionalized sensor surface at different flow rates. Figure displays normalized signal responses from both SPR and QCM measurements.

MP-SPR can be used to study the effect of hydrodynamic flow on the interaction kinetics, making it a valuable tool in biomolecular interaction and targeted drug delivery studies.

Blood stream hydrodynamics is known to be an important pharmacokinetic factor that varies in different vessels and organs throughout the body. Liposomes are used in drug delivery systems to carry drug molecules to the effective site with some products already on the market. Liposomes are also widely studied as drug delivery systems for new drug targeting applications.

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