Publications: Material science


Surface Engineering of Graphene through Heterobifunctional Supramolecular-Covalent Scaffolds for Rapid COVID-19 Biomarker Detection

Publication year: 2021
Authors: Piccinini E., Allegretto J.A., Scotto J., Cantillo A.L., Fenoy G.E., Marmisollé W.A., Azzaroni O.
Published in: CS Applied Materials & Interfaces, 2021, Vol. 13(36), p. 43696–43707
Graphene is a two-dimensional semiconducting material whose application for diagnostics has been a real game-changer in terms of sensitivity and response time, variables of paramount [...]

Lubricin-Inspired Loop Zwitterionic Peptide for Fabrication of Superior Antifouling Surfaces

Publication year: 2021
Authors: Chuanxi Li 1,2, Yinqiang Xia 3, Chunjiang Liu 1, Renliang Huang 4, Wei Qi 1, Zhimin He 1, Rongxin Su 1,4
Published in: ACS Applied Materials & Interfaces, 2021, Vol. 13(35), p. 41978–41986
Biofouling represents great challenges in many applications, and zwitterionic peptides have been a promising candidate due to their biocompatibility and excellent antifouling performance. Inspired by lubricin, [...]

Real-time adsorption of optical brightening agents on cellulose thin films

Publication year: 2021
Authors: C. Sampl a,b, S.Eyley c, W. Thielemans c, U.Hirn a,b,1, S.Spirk a,b
Published in: Carbohydrate Polymers, Vol. 261 (2021), 117826
Optical brightening agents (OBAs) are commonly used in textile and paper industry to adjust product brightness and color appearence. Continuous production processes lead to short residence time of the dyes in the fiber suspension, [...]

Rapid and Oriented Immobilization of Laccases on Electrodes via a Methionine-Rich Peptide

Publication year: 2021
Authors: Haiyang Cui a,b, Lingling Zhang a, Dominik Söder b, Xiaomei Tang a, Mehdi D. Davari a, Ulrich Schwaneberg a,b
Published in: ACS Catalysis, 2021, Vol. 11 (4), p. 2445–2453
Different from other laccases, copper efflux oxidase (CueO) from Escherichia coli possesses an additional methionine-rich segment (MetRich), which is generally considered to be detrimental to its oxidase activity. Herein, we reveal that [...]

Oxidized xylan additive for nanocellulose films – A swelling modifier

Publication year: 2021
Authors: Palasingh Ch. a, Ström A. a, Amer H. b,c, Nypelö T. a,d
Published in: International Journal of Biological Macromolecules, Vol. 180, p. 753-759
Polymeric wood hemicelluloses are depicted to join cellulose, starch and chitosan as key polysaccharides for sustainable materials engineering. However, the approaches to incorporate hemicelluloses in [...]

Control of Polymer Brush Morphology, Rheology, and Protein Repulsion by Hydrogen Bond Complexation

Publication year: 2021
Authors: Andersson J. 1, Ferrand-Drake del Castillo G. 1, Bilotto P. 2, Höök F. 3, Valtiner M. 2, Dahlin A. 1
Published in: Langmuir, 2021, Vol. 37 (16), p. 4943–4952
Polymer brushes are widely used to alter the properties of interfaces. In particular, poly(ethylene glycol) (PEG) and similar polymers can make surfaces inert toward biomolecular adsorption. Neutral hydrophilic [...]

Unraveling the Mechanism and Kinetics of Binding of an LCI-eGFP-Polymer for Antifouling Coatings

Publication year: 2021
Authors: Soeder E. 1,2, Garay-Saramiento S. 1,3, Rahimi K. 1, Obstals F. 1,2, Dedisch S. 1,3, Haraszti T. 1, Davari M.D. 3, Jakob F. 1,3, Hess C. 4, Schwaneberg U. 1,3, Rodriguez-Emmenegger C. 1
Published in: Macromolecular Bioscience, 2021, 2100158
The ability of proteins to adsorb irreversibly onto surfaces opens new possibilities to functionalize biological interfaces. Herein, the mechanism and kinetics of adsorption of protein-polymer macromolecules [...]

Effect of Hydrophobicity and Charge Separation on the Antifouling Properties of Surface-Tethered Zwitterionic Peptides

Publication year: 2021
Authors: Chuanxi Li 1,2,3,4, Minglun Li 2, Wei Qi 2,3, Rongxin Su 1,3,5, Jing Yu 2
Published in: Langmuir, 2021, Vol. 37(28), p. 8455–8462
Zwitterionic peptides emerge as a class of highly effective antifouling material in a wide range of applications such as biosensors, biomedical devices, and implants. We incorporated [...]

Tunable layer-by-layer films containing hyaluronic acid and their interactions with CD44

Publication year: 2020
Authors: Amorim, Pashkuleva I. ab, Reis C. defg, Reis, Pires R. abc
Published in: Journal of Materilals Chemistry, 2020, issue 17
We report on the development of layer-by-layer (LbL) constructs whose viscoelastic properties and bioactivity can be finely tuned by using polyanions of different size and/or crosslinking. As a polyanion we used hyaluronic acid (HA) – a multi-signaling biomolecule whose bioactivity depends on its molecular weight.

Acceleration of biofilm formation in start-up of sequencing batch biofilm reactor using carriers immobilized with Pseudomonas stutzeri strain XL-2

Publication year: 2020
Authors: Zhang P., Ding X., Zhao B. ⁎, An Q., Guo J.S.
Published in: Bioresource Technology, 2020, vol. 314
P. stutzeri strain XL-2 initially immobilized on polypropylene carriers accelerated the biofilm formation in startup of sequencing batch biofilm reactor (SBBR) (denoted R1). The biofilm formation in R1 was approximately completed in 36 days, which was shorter than that of 48 days in an identical SBBR (denoted R2) without strain XL-2.P. stutzeri strain XL-2 initially immobilized on polypropylene carriers accelerated the biofilm formation in startup of sequencing batch biofilm reactor (SBBR) (denoted R1). The biofilm formation in R1 was approximately completed in 36 days, which was shorter than that of 48 days in an identical SBBR (denoted R2) without strain XL-2.P. stutzeri strain XL-2 initially immobilized on polypropylene carriers accelerated the biofilm formation in startup of sequencing batch biofilm reactor (SBBR) (denoted R1). The biofilm formation in R1 was approximately completed in 36 days, which was shorter than that of 48 days in an identical SBBR (denoted R2) without strain XL-2.[...]

Following in Situ the Degradation of Mesoporous Silica in Biorelevant Conditions: At Last, a Good Comprehension of the Structure Influence

Publication year: 2020
Authors: Bindini E. 1,2, Chehadi Z. 1, Faustini M. 1, Albouy P. 3, Grosso D. 4, Cattoni A. 2, Chanéac C. 1, Azzaroni O. 5, Sanchez C. 1, Boissiè C. 1
Published in: ACS Applied Materials and Interfaces, 2020, Vol.12, p.13598–13612
Mesoporous silica nanoparticles (MSNs) have seen a fast development as drug delivery carriers thanks to their tunable porosity and high loading capacity. The employ of MSNs in biomedical applications requires a good understanding of their degradation behavior both to control drug release and to assess possible toxicity issues on human health.[...]

CVD-grown Graphene-on-Au characterization and sensing using Kretschmann-based SPR

Publication year: 2020
Authors: Jamil N.A.1, Mei G.S.1, Zain A.R. 1,2, Hewak D. 3, Huang C-C. 3, Mohamed M.A. 1, Majlis B.Y. 1, Menon P.S.1,*
Published in: Electron Devices Technology and Manufacturing Conference (EDTM), IEEE
A Kretschmann-based surface plasmon resonance (SPR) sensing method was used to determine the refractive index and thickness of graphene thin films. The measured complex refractive index (n,k) values of graphene on Au at 670 nm and 785 nm wavelength are 2.85, 0.74 and 3.1, 1.19 respectively. In further analysis, the analysis of sensing performance of graphene on Au SPR sensor for ethanol detection was obtained using Finite Difference Time Domain (FDTD) method.[...]

PEDOT-polyamine composite films for bioelectrochemical platforms -flexible and easy to derivatize

Publication year: 2020
Authors: Sappia L. +a, Piccinini E. +a, von Binderling C. a, Knoll W. bcd, Marmisollé W. *a, Azzorini O. *acd
Published in: Material Sciece and Engineering: C, 2020, Vol. 109, p.110575
We report a straightforward route for the preparation of flexible, electrochemically stable and easily functionalizable poly(3,4-ethylenedioxythiophene) (PEDOT) composite films deposited on PET foils as biosensing platforms. For this purpose, poly(allylamine) hydrochloride (PAH) was blended with PEDOT to provide amine-bearing sites for further biofunctionalization as well as to improve the mechanical properties of the films.[...]

Surface Preconditioning Influences the Antifouling Capabilities of Zwitterionic and Nonionic Polymer Brushes

Publication year: 2020
Authors: Víšová I. 1, Vrabcová M. 1, Forinová M. 1, Zhigunová Y. 1, Mironov V. 1, Houska . 1, Bittrich E. 2, Eichhorn K. 2, Hashim H. 3,4, Schovánek P. 1,5, Dejneka A. 1, Vaisocherová - Lísalová H. 1
Published in: Langmuir, 2020, Vol. 36, 29, 8485–8493
Polymer brushes not only represent emerging surface platforms for numerous bioanalytical and biological applications but also create advanced surface-tethered systems to mimic real-life biological processes. In particular, zwitterionic and nonionic polymer brushes have been intensively studied because of their extraordinary resistance to nonspecific adsorption of biomolecules (antifouling characteristics) as well as the ability to be functionalized with bioactive molecules.[...]

Modulation of Living Cell Behavior with Ultra‐Low Fouling Polymer Brush Interfaces

Publication year: 2020
Authors: Víšová I., Smolková B., Uzhytchak M., Vrabcová M., Zhigunova Y., Houska M. ,Surman F., de los Santos Pereira A.,Lunov O., Dejneka A., Vaisocherová‐Lísalová H.
Published in: Macromolecular Bioscience, 2020, Vol. 20, 3, p. 1900351
Ultra‐low fouling and functionalizable coatings represent emerging surface platforms for various analytical and biomedical applications such as those involving examination of cellular interactions in their native environments. Ultra‐low fouling surface platforms as advanced interfaces enabling modulation of behavior of living cells via tuning surface physicochemical properties are presented and studied.[...]

Gamma estimator of Jarzynski equality for recovering binding energies from noisy dynamic data sets

Publication year: 2020
Authors: Zhifeng Kuang 1, Kristi M.Singh 1, Daniel J.Oliver 2, Patrick B.Dennis 1, Carole C.Perry 2, Rajesh R.Naik 1
Published in: Nature Communications, Vol. 11, Article number: 5517 (2020)
A fundamental problem in thermodynamics is the recovery of macroscopic equilibrated interaction energies from experimentally measured single-molecular interactions. The Jarzynski equality forms [...]

Structures and Antifouling Properties of Self-Assembled Zwitterionic Peptide Monolayers: Effects of Peptide Charge Distributions and Divalent Cations

Publication year: 2020
Authors: Chuanxi Li 1,2,3, Chunjiang Liu 1, Minglun Li 2, Xin Xu 2, Shuzhou Li 2, Wei Qi 1,3, Rongxin Su 1,3, Jing Yu 2
Published in: Biomacromolecules, 2020, Vol. 21 (6), p. 2087–2095
Zwitterionic peptides are great candidates as antifouling coating materials in many biomedical applications. We investigated the structure and antifouling properties f surface-tethered zwitterionic peptide monolayers [...]

Multilayer Density Analysis of Cellulose Thin Films

Publication year: 2019
Authors: Sampl C. 1,2ʈ, Niegelhell K. 1,2ʈ, Reishofer D. 1ʈ, Resel R. 3ʈ, Spirk S. 1,2*ʈ, Hirn U. 1,2ʈ
Published in: Biopolymer Thin Films and Coatings
An approach for the multilayer density analysis of polysaccharicle thin films at the example of cellulose is presented. In detail, a model was developed for the evaluation of the density in different layers across the thickness direction of the film.[...]

Continuous assembly of supramolecular polyamine–phosphate networks on surfaces: preparation and permeability properties of nanofilms

Publication year: 2019
Authors: Agazzi M.L. a, Herrera S.E. a, Cortez M.L. a, Marmisollé W.A. a, von Bilderling C. a,b, Pietrasanta L.I. b,c, Azzaroni O. *a
Published in: Soft Matter, 2019, 15, p. 1640-1650
Supramolecular self-assembly of molecular building blocks represents a powerful “nanoarchitectonic” tool to create new functional materials with molecular-level feature control. Here, we propose [...]

Enzyme Immobilization in Polyelectrolyte Brushes: High Loading and Enhanced Activity Compared to Monolayers

Publication year: 2019
Authors: del Castillo G.F-D. a, Koenig M. b, Mueller M. b, d, Eichhorn K.-J. b, Stamm M. b,d, Uhlmann P. b,c, Dahlin A. a
Published in: Langmuir, 2019, Vol. 35, p. 3479-3489
Catalysis by enzymes on surfaces has many applications. However, strategies for efficient enzyme immobilization with preserved activity are still in need of further development. [...]