Surface Plasmon Resonance on Nanoscale Organic Films

Publication year: 2010
Authors: Willem M. Albers and Inger Vikholm-Lundin

VTT Technical Research Centre of Finland, Microtechnologies and Sensors, Molecular Sensors, P.O. Box 1300, FIN-33101 Tampere, Finland

Published in: Nano-Bio-Sensing, 1st ed, Chapter 4, Springer 2010

Surface  Plasmon  Resonance  (SPR)  has  evolved  over  the  past  20 years  into  a  very versatile  detection  method,  particularly in  biosci- ence  applications.  Not  only  the  scientific  literature  has  greatly  expanded, but also various commercial vendors of instrumentation, detection chips and reagents have emerged. In the scientific sphere the accent  lies more and more on fabrication of nanostructures with interesting optical behavior (plasmonics), while in the R&D area there are many new miniaturization efforts and combination with other detection methods, such as electrochemistry and quartz crystal micro- balance QCM. The present chapter will focus on the latest developments in making functional biochemical coatings for SPR detection as well as review the basic theory behind the detection techniques.

MP-SPR keywords: