Publications: Biosensors

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Surface plasmon resonance biosensor with high anti-fouling ability for the detection of cardiac marker troponin T

Publication year: 2011
Authors: J.T. Liu a, C.J. Chen b, T. Ikoma c, T. Yoshioka c, J.S. Cross d,e, S.-J.Chang a, J.-Z. Tsai b, J. Tanaka c
Published in: Analytica Chimica Acta, 2011, Vol. 703(1), p. 80-86
Designing a surface recognition layer with high anti-fouling ability, high affinity, and high specificity is an important issue to produce high sensitivity biosensing transducers. In this study, a self-assembled monolayer (SAM) consisting of a homogeneous mixture of oligo(ethylene glycol) (OEG)-terminated alkanethiolate and mercaptohexadecanoic acid (MHDA) on Au was employed for immobilizingtroponin T antibody and applied in detecting cardiac troponin T by using surface plasmon resonance (SPR). [...]

Development of diagnostic SPR based biosensor for the detection of pharmaceutical compounds in saliva

Publication year: 2010
Authors: Susanna Sonny, Adama M. Sesay, Vesa Virtanen
Published in: Proc. SPIE 7376, Laser Applications in Life Sciences, 737605
The aim of the study is to develop diagnostic tests for the detection of pharmaceutical compounds in saliva. Oral fluid is increasingly being considered as an ideal sample matrix. It can be collected non-invasively and causes less stress to the person being tested. [...]

The Development of a diagnostic test for the detection of drugs in saliva using a disposable sample preparation Microfluidic cartridge

Publication year: 2010
Authors: Sesay A M.1, Krühne U.2, Sonny S.3, Lund Olesen T.4, Virtanen V.5
Published in: µTAS 2010 Groningen (2010), Verpoorte, S. et al.(Eds.), 1520-1522pp ISBN 978-0-9798064-3-8
In this paper we report on the development of a diagnostic test for the detection of illegal drugs in saliva [...]

Affinity Interaction between Hexamer Peptide Ligand HWRGWV and Immunoglobulin G Studied by Quartz Crystal Microbalance and Surface Plasmon Resonance

Publication year: 2010
Authors: Fei Sen; Under the direction of Dr. Ruben G. Carbonell
Published in: Ph.D Dissertation, 2010, Chemical Engineering
SHEN, FEI. Affinity Interaction between Hexamer Peptide Ligand HWRGWV and Immunoglobulin G Studied by Quartz Crystal Microbalance and Surface Plasmon Resonance. (Under the direction of Dr. Ruben G. Carbonell.) Immunoglobulins (Ig), also referred to as antibodies, act as protective agents against pathogens trying to invade an organism. Human immunoglobulin G (hIgG), as the most prominent immunoglobulin presented in serum and other human fluids, has broad applications in fields like immunotherapy and clinical diagnostics. [...]

Surface Plasmon Resonance on Nanoscale Organic Films

Publication year: 2010
Authors: Willem M. Albers and Inger Vikholm-Lundin
Published in: Nano-Bio-Sensing, 1st ed, Chapter 4, Springer 2010
Surface Plasmon Resonance (SPR) has evolved over the past 20 years into a very versatile detection method, particularly in biosci- ence applications. Not only the scientific literature [...]

Surface plasmon resonance analysis for detecting non-structural protein 1 of dengue virus in Indonesia

Authors: Widoretno 1 2, Sjahrurachman A. 3, Dewi B.E. 4, Lischer K. 5 6, Pratami D.K. 7, Flamandita D. 5, Sahlan M. 5 6
Published in: Saudi Journal of Biological Sciences, 2020, Vol. 8, p.1931-1937
Dengue is an acute febrile disease caused by dengue virus (DENV) that is transmitted by Aedes sp., which causes serious health conditions in many countries. Non-structural protein 1 (NS1) is a co-factor for the RNA replication of this virus, which represents a new strategy for the identification of dengue. Prompt and accurate laboratory diagnosis of this infection is required to assist in patient triage and management, as well as prevent the spread of this infection.[...]