Publications: Biosensors

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Urea and creatinine detection on nano-laminated gold thin film using Kretschmann-based surface plasmon resonance biosensor

Publication year: 2018
Authors: Menon P.S., Said F.A., Mei G.S., Berhanuddin D.D., Umar A.A., Shaari S., Majlis B.Y.
Published in: PLoS One, 2018, Vol. 13 (7)
This work investigates the surface plasmon resonance (SPR) response of 50-nm thick nano-laminated gold film using Kretschmann-based biosensing for detection of urea [...]

Two-dimensional label-free affinity analysis of tumor-specific CD8 T cells with a biomimetic plasmonic sensor

Publication year: 2018
Authors: Soler M. 1, Li X. 1, John-Herpin A. 1, Schmidt J. 2, Coukos G. 2, Altug H. 1
Published in: ACS Sensors, 2018
The screening and analysis of T cells functional avidity for specific tumor-associated antigens is crucial for the development of personalized immunotherapies against cancer. The affinity [...]

Enzyme Multilayers on Graphene-Based FETs for Biosensing Applications

Publication year: 2018
Authors: Bliem C. a, Piccinini E. b, Knoll W. a, Azzaroni O. b
Published in: Methods in Enzymology, 2018, Vol. 609, p. 23-46
Electrochemical sensors represent a powerful tool for real-time measurement of a variety of analytes of much significance to different areas, ranging from clinical diagnostics to food technology. [...]

Angular scanning and variable wavelength surface plasmon resonance allowing free sensor surface selection for optimum material- and bio-sensing

Publication year: 2018
Authors: Lakayan D. a, b, Tuppurainen J. c, d, Albers M. c, d, van Lint M. J. e, van Iperen D. J. f, Weda J. J. A. g, Kuncova-Kallio J. c, d, Somsen G. W. a, Kool J. a
Published in: Sensors and Actuators B: Chemical, Vol. 259, 15, 2018, p. 972–979
A variable-wavelength Kretschmann configuration surface plasmon resonance (SPR) apparatus with angle scanning is presented. The setup provides the possibility of [...]

Stable, nanometer‐thick oxygen‐containing plasma polymer films suited for enhanced biosensing

Publication year: 2018
Authors: Hegeman D. 1, Indutnyi I. 2, Zajickova L. 3,4, Makhneva E. 3,4, Farka Z. 3, Ushenin Y. 2, Vandenbossche M. 1
Published in: Plasma Processes and Polymers, 2018, e1800090
Stable surface functionalization is required in many applications such as in biosensing. For this purpose, hydrocarbon‐based plasma polymer films (PPFs) were investigated by controlling cross‐linking [...]

A facile molecularly imprinted polymer-based fluorometric assay for detection of histamine

Publication year: 2018
Authors: Feng X., Ashley J., Zhou T., Halder A., Sun Y.
Published in: RSC Advances, 2018, Vol. 8, Issue 5, p. 2365
Histamine is a biogenic amine naturally present in many body cells. It is also a contaminant that is mostly found in spoiled food. The consumption of foods containing high levels [...]

Affinity profiling of monoclonal antibody and antibody-drug-conjugate preparations by coupled liquid chromatography-surface plasmon resonance biosensing

Publication year: 2018
Authors: Lakayan D. 1,2, Haselberg R. 1, Gahoual R. 1,3, Somsen G.W. 1, Kool J. 4
Published in: Analytical and Bioanalytical Chemisry, 2018, p. 1-12
Monoclonal antibodies (mAbs) and antibody-drug conjugates (ADCs) are highly potent biopharmaceuticals designed for targeted cancer therapies. mAbs and ADCs can undergo modifications during [...]

On the Importance of Controlling Film Architecture in Detecting Prostate Specific Antigen

Publication year: 2018
Authors: Graça J. S. a, Miyazaki C. M. a, Shimizu F. M. b, Volpati D. c, Mejía-Salazar J. R. b, Oliveira O.N. Jr. b, Ferreira M. a
Published in: Applied Surface Science, 2018, Vol. 434, p. 1175-1182
Immunosensors made with nanostructured films are promising for detecting cancer biomarkers, even at early stages of the disease, but this requires control of film architecture to preserve [...]

A DNA–nanoparticle actuator enabling optical monitoring of nanoscale movements induced by an electric field

Publication year: 2018
Authors: Tapio K. a, Shao D. a, Auer S. b, Tuppurainen J. c, Ahlskog M. a, Hytönen V.P. b, Toppari J.J. a*
Published in: Nanoscale, 2018, Vol. 10, p. 19297-19309
Merging biological and non-biological matter to fabricate nanoscale assemblies with controllable motion and function is of great interest due to its potential application, for example, in diagnostics and biosensing. [...]

Spin coated chitin films for biosensors and its analysis are dependent on chitin-surface interactions

Publication year: 2018
Authors: Casteleijn M. G. a, Richardson D. a, Parkkila P. a, Granqvist N. b, Urtti A. a, c, Viitala T. a
Published in: Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2018, Vol. 539, p. 261-272
Chitin, abundant in nature, is a renewable resource with many possible applications in bioengineering. Biosensors, capable of label-free and in-line evaluation, play an important role in the investigation of [...]

Label-free biosensors in the field of stem cell biology

Publication year: 2018
Authors: Fathi F. a, Rahbarghazi R. b, c, Rashidi M.-R. a, d
Published in: Biosensors and Bioelectronics, 2018, Vol. 101, p. 188-198
A great body of evidence unveiled the existence of different stem cell types in various tissues with efficient capability for self-renewal and differentiation. Characterization and enumeration [...]

Kinetic and thermodynamic studies of bovine serum albumin interaction with ascorbyl palmitate and ascorbyl stearate food additives using surface plasmon resonance

Publication year: 2018
Authors: Fathi F. a, Mohammadzadeh-Aghdash H. b, c, Sohrabi Y. b, c, Dehghan P. b, Ezzati J. N. D. a
Published in: Food Chemistry, 2018, Vol. 246, p.228-232
Ascorbyl palmitate (AP) and ascorbyl stearate (AS) are examples of food additives, which have extensive use in food industry. In this study, we evaluated the interaction of bovine serum albumin (BSA) with [...]

Immuno-biosensor for Detection of CD20-Positive Cells Using Surface Plasmon Resonance

Publication year: 2017
Authors: Shanehbandi D. 1,2, Majidi J. 1, Kazemi T. 1,2, Baradaran B. 1, Aghebati-Maleki L. 1,2, Fathi F. 2,3, Ezzati Nazhad Dolatabadi J. 3
Published in: Advanced Pharmaceutical Bulletin, 2017, Vol. 7 (2), p.188-194
Purpose: Surface plasmon resonance (SPR) sensing confers a real-time assessment of molecular interactions between biomolecules and their ligands. This approach is highly sensitive [...]

Characterization of IFN-γ Detection and Electrochemical Proximity Assay by a Novel Multi-Parametric/Multimodal Spectroscopy Apparatus

Publication year: 2017
Authors: Zhou L., Chin B. A., Simonian A. L.*
Published in: ECS Transactions, 2017, Vol. 80, Issue 10, p. 1565-1570
Functional interfaces play a vital role in biosensing, which requires proper allocation, orientation, conformation, activities and stability to achieve high affinity and stability of the biomolecules. However, the characterization [...]

Characterization of Covalently Bound Anti-Human Immunoglobulins on Self-Assembled Monolayer Modified Gold Electrodes

Publication year: 2017
Authors: Holzer B. 1, Manoli K. 1, Ditaranto N. 1,2, Macchia E. 1, Tiwari A. 1, Di Franco C. 3, Scamarcio G. 3,4, Palazzo G. 1,2, Torsi L. 1,2
Published in: Advanced Biosystems, 2017
Bioconjugated gold surfaces constitute interesting platforms for biosensing applications. The immobilization of antibodies such as anti-immunoglobulin G and M (anti-IgG and anti-IgM) [...]

Graphene and graphene oxide for biosensing

Publication year: 2017
Authors: Kubesa O. 1, Horackova V. 2, Moravec Z. 2,3, Farka Z. 2, Skladal P. 1,2
Published in: Monatshefte für Chemie, 2017
Graphene-based nanomaterials attract large attention in electrochemistry due to their unique properties. Reliable method to modify electrodes by graphene is necessary to obtain desired improvement. In this work, [...]

Ultrasensitive detection of nucleic acids and proteins using quartz crystal microbalance and surface plasmon resonance sensors based on target-triggering multiple signal amplification strategy

Publication year: 2017
Authors: Sun W. 1, Song W. 2, Guo X. 3, Wang Z. 1
Published in: Analytica Chimica Acta, 2017, Vol. 978, p. 42-47
In this study, quartz crystal microbalance (QCM) and surface plasmon resonance (SPR) sensors were combined with template enhanced hybridization processes (TEHP), rolling circle amplification (RCA) [...]

Electrochemical Proximity Assay of Platelet-Derived Growth Factor through Combined Surface Plasmon Resonance, Electrochemistry, and Fluorescence Spectroscopy Approach

Publication year: 2017
Authors: Zhou L. a, Chin B.A. a, Simonian A.L. b
Published in: ECS Transactions, 2017, Vol. 77, Issue 11, p. 1809-1814
Platelet-derived growth factor (PDGF) is a potential cancer marker, which plays an important role in early detection of cancers. Due to its trace amounts in blood sample, it is difficult to be detected. [...]

Label-free evaluation of carbon nanoparticles in Layer-by-Layer self-assembled enzyme-based biosensors

Publication year: 2017
Authors: David M. a, Florescu M. b, Barsan M. M. c, Brett M.A.C. c
Published in: Procedia Technology, Vo. 27, 2017, p. 304-305
The immobilization of biomolecules and the enhancement of the electron transfer are important factors regarding the performances of the enzyme-based biosensors. Layer-by-layer (LbL) strategies can be effectively used [...]

A Surface Plasmon Resonance Histamine Sensor Based on an Electropolymerized Molecularly Imprinted Polymer (E-MIP)

Publication year: 2017
Authors: Hubilla F.A.D., Mabilangan A.I., Advincula R.C., del Mundo F.R.
Published in: MATEC Web of Conferences, Vol. 95, 2017
In this paper, histamine sensing by surface plasmon resonance (SPR) spectroscopy using an electropolymerized molecularly imprinted polymer (E-MIP) of functionalized polyterthiophene and histamine is reported. [...]