Polymer characterization using MP-SPR
- Adsorption studies and layer thickness

Application Note #149


Figure 1
. Schematic view of the adsorption of block copolymers onto nanocellulose surfaces and of serum components onto the poly(ethylene glycol) polymer brushes, as studied using MP-SPR.

Polymers are extensively studied and often interactions play a key role in the product functionality. Two separate polymer interaction studies were conducted using label-free real-time Multi-Parametric Surface Plasmon Resonance (MP-SPR). Functionalization of nanocellulose surfaces was performed by adsorption of block copolymers. The efficacy of anti-fouling of the PEG-based polymer brushes was quantified by measuring adsorption of serum samples. Based on the MP-SPR measurements, polymers were further characterized in terms of thickness andadsorbed mass. Nanocellulose functionalization was confirmed to be successful and -OH terminated 10 kDa PEG was found to be the best anti-fouling coating, producing 99% resistance.

Recommended instrument for this application:

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200 OTSO 400 KONTIO 210A VASA  410A KAURIS  220A NAALI 420A ILVES 
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Further reading

  • If you are interested in reading more, see AN#128 about thickness and refractive index of thin films and AN#155 about material swelling studies in vapor.

  • Do you want to find out how to calculate thickness out of MP-SPR measurements? Click here.

  • Do you want to see how MP-SPR instruments work? Click here.

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