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Antibody-mediated biorecognition of myelin oligodendrocyte glycoprotein: computational evidence of demyelination-related epitopes

Publication year: 2019
Authors: Ierich J.C.M. 1,2, Brum D.G. 3, Moraes A.S. 1,2, Higa A.M. 1,2, Garcia P.S. 1,2, Miyazaki C.M. 4, Ferreira M. 4, Peroni L.A. 5, Oliveira G.S. 6, Franca E.F. 6, Freitas L.C.G. 7, Leite F.L. 8
Published in: Scientific Reports, 2019, Vol. 9, Issue 1, p. 2033
Antigen-antibody interaction is crucial in autoimmune disease pathogenesis, as multiple sclerosis and neuromyelitis optica. Given that, autoantibodies are essential [...]

Continuous assembly of supramolecular polyamine–phosphate networks on surfaces: preparation and permeability properties of nanofilms

Publication year: 2019
Authors: Agazzi M.L. a, Herrera S.E. a, Cortez M.L. a, Marmisollé W.A. a, von Bilderling C. a,b, Pietrasanta L.I. b,c, Azzaroni O. *a
Published in: Soft Matter, 2019, 15, p. 1640-1650
Supramolecular self-assembly of molecular building blocks represents a powerful “nanoarchitectonic” tool to create new functional materials with molecular-level feature control. Here, we propose [...]

ORP2 interacts with phosphoinositides and controls the subcellular distribution of cholesterol

Publication year: 2019
Authors: Koponen A. a, Arora A. a, Takahashi K. b, Kentala H. a, Kivelä A.M. a, Jääskeläinen E. a, Peränen J. b, Somerharju P. c, Ikonen E. b, Viitala T. d, Olkkonen V.M. a,b
Published in: Biochimie, 2019, Vol. 158, p. 90-101
ORP2 is a sterol-binding protein with documented functions in lipid and glucose metabolism, Akt signaling, steroidogenesis, cell adhesion, migration and proliferation. [...]

Use of a Branched Linker for Enhanced Biosensing Properties in IgG Detection from Mixed Chinese Hamster Ovary Cell Cultures

Publication year: 2019
Authors: Islam N. a,b, Gurgel P.V. a,c, Rojas O.J. a,d, Carbonell R.G. a,e
Published in: Bioconjugate Chemistry, 2019, Vol. 30, p. 815−825
Tris(2-aminoethyl)-amine (TREN), a branched amine, was coupled to planar surfaces of alkanethiol self-assembled monolayers (SAMs) to increase [...]

In Silico Discovery and Validation of Neuropeptide-Y-Binding Peptides for Sensors

Publication year: 2019
Authors: Xiao X. 1, Kuang Z. 2, Burke B. J. 2, Chushak Y. 2, Farmer B.L. 2, Mirau P.A 2.*, Naik R.P. 2, Hall C.K.*1
Published in: The Journal of Physical Chemistry B, 2020, Vol. 124, 1, p. 61–68
Wearable sensors for human health, performance, and state monitoring, which have a linear response to the binding of biomarkers found in sweat, saliva, or urine, are of current interest for many applications. A critical part of any device is a biological recognition element (BRE) that is able to bind a biomarker at the surface of a sensor with a high affinity and selectivity to produce a measurable signal response.[...]

Enzyme Immobilization in Polyelectrolyte Brushes: High Loading and Enhanced Activity Compared to Monolayers

Publication year: 2019
Authors: del Castillo G.F-D. a, Koenig M. b, Mueller M. b, d, Eichhorn K.-J. b, Stamm M. b,d, Uhlmann P. b,c, Dahlin A. a
Published in: Langmuir, 2019, Vol. 35, p. 3479-3489
Catalysis by enzymes on surfaces has many applications. However, strategies for efficient enzyme immobilization with preserved activity are still in need of further development. [...]

Design and evaluation of a multiplexed angular-scanning surface plasmon resonance system employing line-laser optics and CCD detection in combination with multi-ligand sensor chips

Publication year: 2019
Authors: Lakayan D. a, Tuppurainen J. c, Suutari T.E. a,d, van Iperen D.J. e, Somsen G.W. a, Kool J. a
Published in: Sensors and Actuators B: Chemical, 2019, Vol. 282, p. 243-250
An angle-scanning Kretschmann configuration SPR instrument allowing multiplexed analysis is presented. Laser light was guided through optics that converted the collimated light into a line-shaped beam, which was [...]

Maleic anhydride and acetylene plasma copolymer surfaces for SPR immunosensing

Publication year: 2019
Authors: Makhneva E. 1,2, Farka Z. 3, Pastucha M. 4,5, Obrusník A. 1,2, Horáčková V. 4, Skládal P. 4,5, Zajíčková L. 1,2
Published in: Analytical and Bioanalytical Chemisry, 2019
We report on the successful application of carboxyl-rich plasma polymerized (PP) films as a matrix layer for bioreceptor immobilization in surface plasmon resonance (SPR) immunosensing. Composition and [...]

Layer‐by‐Layer Formation of Polyamine‐Salt Aggregate/Polyelectrolyte Multilayers. Loading and Controlled Release of Probe Molecules from Self‐Assembled Supramolecular Networks

Publication year: 2019
Authors: Herrera S.E. 1, Agazzi M.L. 1, Cortez M.L. 1, Marmisollé W.A. 1, von Bildering C. 1,2, Azzaroni O. 1
Published in: Macromolecular Chemistry and Physics, 2019
The use of soft materials as building blocks in layer‐by‐layer (LbL) assemblies represent a very appealing and useful approach to enhance the loading capacity of thin films. Here, the capacity of positively charged polyamine‐salt aggregates (PSAs) [...]

Antimicrobial alumina nanobiostructures of disulfide- and triazole-linked peptides: Synthesis, characterization, membrane interactions and biological activity

Publication year: 2019
Authors: Torres L.M.F.C. a, Almeida M.T. a, Santos T.L. a, Marinho L.E.S. a, de Mesquita J.P. a, da Silva L.M. a, dos Santos W.T.P. b, Martins H.R. b, Kato K.C. b, Alves E.S.F. c, Liao L.M. c, .de Magalhães M.T.Q d, de Mendonça F.G. e, Pereira F.V. e, Resende J.M. e, Bemquerer M.P. f, Rodrigues M.A. g, Verly R.M. a
Published in: Colloids and Surfaces B: Biointerfaces , 2019, Vol. 177, p. 94-104
Due to the its physical-chemical properties, alumina nanoparticles have potential applications in several areas, such as nanobiomaterials [...]

Handbook of MP-SPR

Publication year: 2019
Authors: Marquart A., Kuncová-Kallio J., Albers M., Bombera R., Ståhlberg R.
Published in: Handbook of MP-SPR, 2019, Vol. 1, Based on fifth edition of Arnoud Marquart's Surface Plasmon Resonance book
Handbook of Multi-Parametric Surface Plasmon Resonance for Molecular Interaction Analysis - Theory and Practice

Handbook of MP-SPR

Publication year: 2019
Authors: Marquart A., Kuncová-Kallio J., Albers M., Bombera R., Ståhlberg R.
Published in: Handbook of MP-SPR, 2019, Vol. 1
Handbook of Multi-Parametric Surface Plasmon Resonance for Molecular Interaction Analysis - Theory and Practice

Handbook of MP-SPR

Publication year: 2019
Authors: Marquart A., Kuncová-Kallio J., Albers M., Bombera R., Ståhlberg R.
Published in: Handbook of MP-SPR, 2019, Vol. 1
Handbook of Multi-Parametric Surface Plasmon Resonance for Molecular Interaction Analysis - Theory and Practice

Ch. 11: Optical and Acoustic Label-free Instrumentation for Molecular Detection with a Focus on Food

Publication year: 2019
Authors: J. Kuncová-Kallio, S. Auer, A. Spehar, H.H. Qu, D. Spasic, J. Lammertyn
Published in: Rapid Antibody-based technologies is Food Analysis, 2019, Vol. 15, p. 223-255
Food Chemistry, Function and Analysis: Optical and Acoustic Label-free Instrumentation for Molecular Detection with a Focus on Food

Interface Interaction Behavior of Self-Terminated Oligomer Electrode Additives for a Ni-Rich Layer Cathode in Lithium-Ion Batteries: Voltage and Temperature Effects

Publication year: 2019
Authors: Fu-Ming Wang,*,†,‡,§,∥ Tibebu Alemu,† Nan-Hung Yeh,† Xing-Chun Wang,† Yi-Wen Lin,† Chun-Chuan Hsu,† Yung-Jen Chang,† Chia-Hao Liu,† Chiao-I Chuang,† Li-Hao Hsiao,† Jin-Ming Chen,⊥ Shu-Chih Haw,⊥ Wei-Ling Chen,† Quoc-Thai Pham,† and Chia-Hung Su
Published in: ASC Applied Materials and Interfaces
Self-terminated oligomer additives synthesized from bismaleimide and barbituric acid derivatives improve the safety and performance of lithium-ion batteries (LIBs). [...]

Synergy between Zwitterionic Polymers and Hyaluronic Acid Enhances Antifouling Performance

Publication year: 2019
Authors: Yinqiang Xia,† Vahid Adibnia,‡ Cancan Shan,† Renliang Huang,§ Wei Qi,†,# Zhimin He,† Guojun Xie,∥ Mateusz Olszewski,∥ Gregory De Crescenzo,⊥ Krzysztof Matyjaszewski,*,∥ Xavier Banquy,*,‡ and Rongxin Su*,†,#
Published in: Langmuir
Challenges associated with nonspecific adsorption of proteins on sensor surfaces have steered the development of novel antifouling materials and strategies. Inspired by human synovial fluid composition and structure, we designed synergistic antifouling coatings with mixtures of hyaluronic acid (HA) and a zwitterionic bottlebrush polymer (BB). [...]

Refractive Index and Sensing of Glucose Molarities Determined using Au-Cr K-SPR at 670/785 nm Wavelenght

Publication year: 2019
Authors: P. Susthitha Menon*, Budi Mulyanti, Nur Akmar Jamil, Chandra Wulandari, Harbi Setyo Nugroho, Gan Siew Mei, Noor Faizah Zainul Abidin, Lilik Hasanah, Roer Eka Pawinanto & Dilla Duryha Berhanuddin
Published in: Sains Malaysiana 48(6)(2019): 1259–1265

Layer-by-Layer nanostructured films of magnetite nanoparticles and polypyrrole towards synergistic effect on methylparaben electrochemical detection

Publication year: 2019
Authors: Lucas F. de Lima, Cristiane M. Daikuzono, Celina M. Miyazaki, Elisabete A. Pereira, Marystela Ferreira
Published in: Applied Surface Science
The sustained use of cosmetics, hygiene products and medicines containing methylparaben (MeP) can be related to cases of cancer in women and children, which is why it is important to develop simple ways to monitor this compound.

Real-Time Label-Free Targeting Assessment and in Vitro Characterization of Curcumin-Loaded Poly-lactic-co-glycolic Acid Nanoparticles for Oral Colon Targeting

Publication year: 2019
Authors: Mohamed A. Akl,†,‡ Alma Kartal-Hodzic,† Teemu Suutari,† Timo Oksanen,† Isabella Monia Montagner,§ Antonio Rosato,§,∥ Hatem R. Ismael,‡ Mohsen I. Afouna,‡ Paolo Caliceti,⊥ Marjo Yliperttula,†,⊥ Ahmed M. Samy,‡ Francesca Mastrotto,⊥ Stefano Salmaso,⊥ and Tapani Viitala*,†,#
Published in: ASC Omega
The exploitation of curcumin for oral disease treatment is limited by its low solubility, poor bioavailability, and low stability. Surface-functionalized poly-lactic-co-glycolic acid (PLGA) nanoparticles (NPs) have shown promising results to ameliorate selective delivery of drugs to the gastrointestinal tract. [...]

Trypanosoma cruzi Virulence Factors for the Diagnosis of Chagas’ Disease

Publication year: 2019
Authors: Cecilia Yamil Chain,*,† Dênio Emanuel Pires Souto,*,‡ María Laura Sbaraglini,§ Carlos A. Labriola,∥ María Antonieta Daza Millone,† Eduardo Alejandro Ramirez,† José Sebastián Cisneros,† Constanza Lopez-Albizu,⊥ Karenina Scollo,⊥ Lauro T. Kubota,# Andrés Mariano Ruiz,⊥ and María Elena Vela†
Published in: ACS Infectious Diseases
trans-Sialidase and cruzipain are important virulence factors from Trypanosoma cruzi, the etiological agent of Chagas disease, that have highly antigenic domains in their structure and were reported as potential tools for diagnosis of the illness. [...]