96 and 384 well plate automation for life sciences

MP-SPR Navi™ 220A NAALI enables all the measurements as traditional SPR but provides premium quality data with PureKineticsTM and allows measurements of conformation changes. The instrument performs great also with direct measurements of small molecules.

 Features and benefits:

  • Automation of samples from 96 and 384 well plate format allows for unattended runs
  • Software switch for serial and parallel injections
  • Partial loop injections providing minimal sample consumption
  • 4  simultaneous  measurements  in  2  fluidic  channels,  two independent  wavelength  measurements  from  the  same  spot, enabling detection of thickness and refractive index or conformation changes
  • Exceptionally  wide  angular  range 40˚ - 78˚ enables  measurement  of small  organic  molecules,  and  large  proteins,  but  also  metallic nanoparticles and cells. Most importantly, it enables in line bulk effect separation - PureKineticsTM
  • Controlled buffer flow conditions with precise syringe pumps and integrated degasser
  • Software package for convenient control of the instrument and easy analysis of the results. The instrument comes with TraceDrawer for  MP-SPR  Navi™  - a powerful  software  for  determination  of affinity and  kinetic constants and more. MP-SPR Navi™ LayerSolver to determine thickness and RI from multiple wavelength measurements is an optional module.
  • MP-SPR Navi™ instruments utilize optical RI matching elastomer and therefore, sensors are very easy to exchange and also to further analyze with other methods such as AFM or microscopy.

220A NAALI is designed and manufactured in Finland. Its name comes from vast Finnish forests and means an arctic fox.
The older generation of this model was SPR Navi™ 220A.


Check out how to measure α-lactalbumin protein concentration from bovine milk utilizing multi-parametric surface plasmon resonance!

Thanks to multiple wavelengths and scanning angular scans, BioNavis’ unique technology allows measurements of kinetic constants, concentration and competition analysis, affinity and EC50. MP-SPR provides insights into conformation changes of the molecules as well. PureKinetics™ is a unique feature of the MP-SPR Navi instruments that allows to measure the true binding of samples while the bulk signal can be reduced. Crude samples such as 100% serum, saliva or cell medium can be used.

Put yourself in the shoes of a scientist with our GoPro movie!


Contact your local distributor or BioNavis for more information. Request a quotation here.

If you have already a MP-SPR NaviTM system see how to upgrade it to 220A NAALI.

See MP-SPR applications in life science or material science!