MP-SPR can be utilized for layer characterization such as thickness and refractive index (RI) of the deposited layer. In addition to this also binding of molecules to the surface can be determined. This is utilized especially for new materials and coating development, such as barriers for moisture, protein, bacteria,...
Bound mass of the adsorbed molecules can be calculated based on de Feiter equation.
Easy calculation from the MP-SPR response can be performed.
Thickness and refractive index information show also conformation changes on the surface.
See mathematics of SPR for further information on equations governing SPR.
See application examples!
Selecting surface modification for in vitro diagnostic tests
Adsorption of hIgG on cellulose, chitosan and CMC surfaces at pH 5-8 studied with MP-SPR.
New type of point of care devices and other consumer analysis devices need new cost effective and preferably renewable new materials in order to be economically and environmentally feasible. Multi-Parametric Surface Plasmon Resonance can be used to study new material coatings, such as modified cellulose model surfaces, for studying interactions of new materials and analysts.
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