Why choose MP-SPR for nanoparticle characterization?

The most sensitive instrument for real-time adsorption kinetics on surfaces

Owing to its plasmonic principle, MP-SPR is the most sensitive measurement for kinetics on surfaces. This is important in real-time measurements of nanoparticle adsorption kinetics, swelling and release. Even less than a monolayer of nanoparticles or proteins can be detected.


Thickness and refractive index solved simultaneously

Thanks to our multiple wavelength configuration with scanning angular range of almost 40 degrees, MP-SPR is capable of acquiring enough information to solve thickness and refractive index of the layer simultaneously using LayerSolver. This is possible even for nanolaminates.

Ultrathin films from thickness of a few Ångström 

BioNavis has been involved in several industrial projects assessing nanoparticle adsorption onto different surfaces. Resulting nanolayers from 3.5 Å (graphene) up to hundred nanometers were studied for their thickness, optical properties and plasmonics. The MP-SPR method is sensitive to metal thickness, roughness and grain structure, because these properties affect the plasmonic fingerprint that MP-SPR measures.

From dry to wet state with the same configuration

Traditional SPR is developed to work in liquid. On the other hand traditional ellipsometers work the best in air. MP-SPR works in both thanks to the goniometeric configuration. 

Cross-validation with microscopy and modelling is possible

MP-SPR with electrochemistry, fluorescence, or other specialty flow-cell allows for validation of measurements in-situ.

Owing to its oil-free operation, same sample can be measured ex-situ with AFM, SEM or other techniques.

Results from MP-SPR are absolute and therefore, can be directly related to physical properties and validated by established theoretical models can be confirmed also analytically.

MP-SPR measurements do not require vacuum

MP-SPR measurements can be performed at different pH, temperature (15 to 45 °C), electric potential. The measurements do not require vacuum.


Recommended MP-SPR instruments for nanoparticle characterization:

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