MP-SPR for nanoparticle characterization

Nanoparticles are particles between 1 and 100 nanometers in size. In nanotechnology, a particle is defined as a small object that behaves as a whole unit with respect to its transport and properties. Nanoparticle research is currently an area of intense scientific interest due to a wide variety of potential applications in biomedical, optical and electronic fields. 

Nanoparticles are of great scientific interest as they are, in effect, a bridge between bulk materials and atomic or molecular structures. A bulk material should have constant physical properties regardless of its size, but at the nano-scale size-dependent properties are often observed. Thus, the properties of materials change as their size approaches the nanoscale and as the percentage of atoms at the surface of a material becomes significant. For bulk materials larger than one micron, the percentage of atoms at the surface is insignificant in relation to the number of atoms in the bulk of the material. The interesting and sometimes unexpected properties of nanoparticles therefore occur largely due to the large surface area of the material, which dominates the contributions made by the small bulk of the material.

See five reasons to choose MP-SPR for measurements of nanoparticles:

  • The most sensitive instrument for real-time adsorption kinetics on surfaces
  • Thickness and refractive index solved simultaneously using LayerSolver™
  • From dry to wet state with the same configuration
  • Cross-validation with microscopy and modelling is possible
  • Measurements do not require vacuum. Measurement can be performed in organic solvents.

The measurements are performed on model surfaces. We have a wide range of surfaces to choose from, or you can make them in your premises. We are glad to provide our expertise and measure your samples in our facilities.

See key questions about nanoparticles that MP-SPR can answer:

  • How good (effective) is this plasmonic material?
  • Which surface modification of nanoparticles results in the best plasmon / dye-sensitized solar cell? 
  • How reproducible is the coating?
  • How does molecule X interact with nanoparticle Y?
  • How does this surface coating react to different moisture contents in air?
  • What is the adsorption kinetics of nanoparticle X to surfaxe Y?
  • What is the release kinetics of material Z from nanoparticle X?
  • What surface modification of nanoparticle X enters the cell the fastest?

See selected Application Notes to see that MP-SPR works:

  • AN#164 Affinity and kinetics of nanoparticle – protein interaction
  • AN#158 Predicting cellulose nanocrystals dispersibility using MP-SPR
  • AN#156 Nanoparticle uptake by cells measured using MP-SPR
  • AN#140 Self-assembly of gold nanoparticles measured with MP-SPR
  • AN#133 Characterization of atomic layer deposited metal films and nanolaminates
  • AN#116 Characterization of graphene oxide films with MP-SPR
  • AN#112 In situ monitoring of metal-organic framework assembly with MP-SPR

Selected publications:


See five reasons to choose MP-SPR for nanoparticle characterization.