MP-SPR for biosensor development

MP-SPR is an invaluable tool for assay development in fields such as food and feed safety, environmental safety, clinical diagnostics, border control and process control. While part of the research worldwide is dedicated to high-throughput instruments, more and more attention is gained by portable or point-of-care instruments. MP-SPR is an excellent tool for development of portable biosensors. Point-of-care biosensors include typically electrochemical sensors, surface enhance Raman sensors (SERS), ELISA, fluorescence or newly also printed diagnostics.

See five reasons to choose MP-SPR for assay development:

  • Easy ex-situ modification of SPR surfaces
  • Any assay type
  • Any sample
  • Easy validation
  • Microfluidic material testing

For information on electrochemical biosensor development click here.

See five key questions in assay development that MP-SPR can answer:

  • How fast do the molecules X bind with surface A as compared to surface B?
  • What is the optimum surface for my biosensor applications?
  • How does my assay work with crude sample such as serum, saliva, sea water or urine?
  • Is the biosensor that I have designed working better than the previous one?
  • Which coating prevents sample adsorption onto my microfluidic channels?

See a few selected Application Notes to see that MP-SPR works:

  • AN#165 Cellulose fiber-based yarn development for capturing estrogen residues from aqueous matrices with MP-SPR
  • AN#160 Biosensor for bacteria detection from powdered milk
  • AN#151 MP-SPR measurements of soft and hard corona on nanoparticle in 100% serum
  • AN#150 Organophosphonates characterization using MP-SPR
  • AN#145 Virus interaction studies using MP-SPR
  • AN#140 Gold nanoparticles for biosensing
  • AN#132 Immunosensor development - Quantification of binding capacity of biofunctional layer
  • AN#126 Selection of cellulose modification for printed biosensor applications
  • AN#117 Quantitative detection of DNA

Selected publications:

For electrochemical sensor development using MP-SPR, click here.

Printed biosensor development using MP-SPR:

MEMS sensor development using MP-SPR:

Novel coatings to avoid non-specific binding using MP-SPR:

Assay development using MP-SPR:

Improving performance of optical biosensors:

What our users say about MP-SPR for biosensor development:

"It is essential that we can prepare our own biosensing surfaces in-situ and ex-situ and test them with SPR." 
Dr. Adama Sesay, Center for Measurement and Information Systems, University of Oulu, Finland



See five reasons to choose MP-SPR for biosensor development.