Welcome to the experts in Surface Plasmon Resonance
We aim to assist you on your way to absolute and high-quality results may they be in life sciences, biosensors or material sciences. Here we provide an executive summary about the MP-SPR technology, applications and products. More comprehensive information is available in our full website.
Applications of MP-SPR
Multi-Parametric Surface Plasmon Resonance (MP-SPR) is a real-time label-free surface sensitive technique that measures molecular interactions as well as structural changes and layer properties in both dry and wet state.
There are three major application areas of MP-SPR:

LIFE SCIENCES
Drug development (Drug formulation, Controlled drug release, Drug-cell interaction, Nanoparticle targeting, Uptake mechanisms)
Biophysics (Lipid interactions)
LIFE SCIENCES:
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BIOSENSORS
Assay development (Agriculture, Food and feed safety, Environmental, Clinical, Border and Process control).
Development of point-of-care biosensors (EC, SERS, ELISA, fluorescence, printed biosensors, nanoparticles)
BIOSENSORS:
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MATERIAL SCIENCES
New materials and coatings (Antimicrobial, Antireflective surfaces, Filter membranes, Contact lenses, Implants, Graphene, Carbon nanotubes, Green materials, Plasmonic materials,..)
Process optimization of thin film manufacturing (Display technologies, Solar cells, Batteries etc.)
MATERIAL SCIENCES:
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About Multi-Parametric Surface Plasmon Resonance (MP-SPR)
Originally, surface plasmon resonance (traditional SPR) instruments have been developed for molecular interactions only. The technology has been used in biopharmaceutical development for more than 20 years with gold and dextran surfaces. We have pushed the limits of the technology to enable measurements on a number of other surfaces including polymers, graphene, nanoparticles and living cells.
More importantly, MP-SPR enables novel functions:
- Measurements of molecular interactions with PureKinetics™
- Measurements of layer properties with LayerSolver™
Measurements:
Layer properties |
Molecular interactions |
Optical dispersion | Electrochemistry |
Substrates:
MP-SPR expands substrates from traditional layers of gold, dextrans and other thin polymers to cellulose, PS, PET, PMMA, SiO2, TiO2, Al2O3, ITO, graphene, CNT, Pt, Pd and other.
MP-SPR is not limited to the thin films alone. Thanks to its angular scan mode, it is possible to measure even micron thick layers and interactions on them. This MP-SPR can also work with whole living cell monolayers.
Theory of MP-SPR
An incident beam of p-polarized light strikes an electrically conducting gold layer at the interface of a glass sensor with high RI (Refractive Index) and an external medium/sample with low RI. At a given angle, the excitation of surface plasmons takes place resulting in a reduced intensity of the reflected light, which can be seen as a dip in the SPR curve.

Traditional SPR (such as focused beam BIA analysis, SPREETA, imaging SPR) measures only peak minimum at a single wavelength limiting its functionality and applicability. MP-SPR acquires whole SPR curve at multiple wavelengths providing high quality measurements of surface interactions as well as layer properties and enabling PureKinetics™ and LayerSolver™.
More about theory:
How does MP-SPR work? MP-SPR angular scan, MP-SPR nanoparticle interactions, MP-SPR thickness measurements (English only)
How does MP-SPR compare with other techniques? Traditional SPR, ellipsometry, QCM (English only)
Further reading on SPR theory (English only)
About MP-SPR Navi™ Instruments
The first instrument was installed in 2008 and is still in use. The MP-SPR technology was introduced first in 2011, which has enabled a tremendous jump in the capabilities of the instruments as compared to traditional SPR. Our instruments are used by academia and industry in more than 25 countries of the world including USA, Japan, China, Finland but also Turkey and Argentina. The newest generation of our instruments was released in 2015 introducing four main products of MP-SPR Navi™ family:
Previously, our products included also SPR Navi™ 200, 210A and 220A as well as KSV SPR 200.
All instruments are designed and manufactured in Finland.
Specifications of our products (English only)
How do our instruments work? See our videos (English only)

About BioNavis Ltd
We are the only manufacturer of MP-SPR instruments for studies of surface interactions and nanolayer characterization. We believe in:
- Understanding rather than just measuring and that is why absolute results obtained with MP-SPR can be tracked down also analytically
- Versatility rather than one-trick instruments and that is why our instruments can be used also in your future projects and those of your neighboring labs
- Co-operation to advance science and translation of research results to industry
BioNavis Ltd is a privately held company based in Tampere, Finland.
More information
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