TECHNOLOGY
WHAT IS MP-SPR?
MP-SPR - The next generation of SPR. For the past 20 years SPR has been used for biomolecular interaction analysis. Now MP-SPR broadens the application range to biophysical studies, and biomaterial studies. Thickness and refractive index can be measured both on nanolayers (Å-100 nm) and on thick layers (350 nm – microns). With additional lasers, a singular solution can be found without known RI or thickness! Materials can include metals, semiconductors and dielectrics, such as Al2O3, SiO2, hydrogels, nylon, cellulose, PS, PP, PET,…
BASICS OF SPR THEORY
Comparison of instruments based
|
SPR Navi™ instruments |
Other SPR instruments |
|
Molecular interactions |
Yes |
Yes |
|
Absorbed mass |
Yes |
When dn/dc known |
|
Film thickness analysis |
Yes |
Limited |
|
Film optical properties |
Yes |
Limited |
|
Simultaneous dn/dc measurement |
Yes |
No |
|
Measurement in gas and liquid phase |
Yes |
Some instruments |
|
Combining with external equipment |
Simple |
Sometimes possible |
|
Electrochemistry |
Yes |
Some instruments |
|
Additional set of lasers for wide angular scans |
Yes |
No |
|
Sensor slides |
Metals, metal oxides, hydrogels |
Gold and hydrogels |
*) Traditional SPR is represented by instruments with focused beam, fixed angle set-up.