Self-assembly of gold nanoparticles measured with MP-SPR

Application Note #140


"Whole SPR curves during gold nanoparticle deposition, measured with 785nm wavelength" 


Gold nanoparticles (AuNPs) exhibits interesting optical and electronic properties that find application in sensors, catalysis, electronics, photonics, solar cells, cancer diagnosis and therapy. Controlled attachment of Au nanoparticles at a solid interface is required for many of these applications. 

Gold  nanoparticles  were  immobilized  on  a  monolayer  self-assembled on gold. Functional groups on the chain ends of the monolayer facilitated an anchoring of gold nanoparticles to the layer. Multi-Parametric Surface Plasmon Resonance (MP-SPR) enabled a real-time measurement of the binding of the gold nanoparticles to the surface layer. The whole SPR curve can be monitored which enables observing not only the SPR peak minimum position during binding of the nanoparticles to the surface layer, but also the shift in peak minimum intensity and total internal reflection (TIR). AuNPs exhibit strong surface plasmon resonances and even a large response could be observed by MP-SPR.

Recommended instrument for this application:

200_otso_small.jpg 210_vasa_small.jpg 220A_naali_small.jpg

 green-tick.png     green-tick.png    green-tick.png                

Further reading

  • If you are interested in reading more about characterization of thin metal films, you may also view AN#146 about characterization of graphene. If you are interested in nanoparticles, we recommended AN#152 about drug delivery nanoparticles and AN#156 about nanoparticle uptake by living cells.

  • Do you want to see how MP-SPR instruments work? Click here.

  • Do you want to see comparison of MP-SPR instruments? Click here.

  • Here are a few publications you can have a look at.


Back to all Application Notes