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Detection of transferrin by using a surface plasmon resonance sensor functionalized with a boronic acid monolayer

Publication year: 2017
Authors: Yanchao Mayang 1,2, Xiwen He 1,2, Langxing Chen 1,2, Yukui Zhang 1,2,3
Published in: Microchimica Acta, 2017, Vol. 184 (8), p. 2749–2757
A surface plasmon resonance sensor whose surface has been modified with boronic acid groups was developed in order to bind and detect transferrin. 4-Mercaptophenylboronic acid (4-MPBA) was utilized [...]

Dangerous liaisons: anion-induced protonation in phosphate-polyamine interactions and their implications for charge states of biologically relevant surfaces

Publication year: 2017
Authors: Laucirica G., Marmisollé W.A., Azzaroni O.
Published in: Physical Chemistry Chemical Physics, 2017, Vol. 19 (12), p. 8612-8620
Although not always considered a preponderant interaction, amine-phosphate interactions are omnipresent in multiple chemical and biological systems. [...]

Effect of Ionic Strength and Surface Charge Density on the Kinetics of Cellulose Nanocrystal Thin Film Swelling

Publication year: 2017
Authors: Reid M.S. 1, Kedzior S.A. 1, Villalobos M. 2, Cranston E.D. 1
Published in: Langmuir, 2017, Vol. 33 (30), p. 7403–7411
This work explores cellulose nanocrystal (CNC) thin films (<50 nm) and particle–particle interactions by investigating film swelling in aqueous solutions with varying ionic strength [...]

Differential Effect of Bilayer Thickness on Sticholysin Activity

Publication year: 2017
Authors: Palacios-Ortega J. 1, 2, García-Linares S. 1, 2, Rivera-de-Torre E. 1, Gavilanes J.G. 1, Martínez-del-Pozo A. 1, Slotte J.P. 2
Published in: Langmuir, 2017, Vol. 33 (41), p. 11018–11027
In this study, we examined the influence of bilayer thickness on the activity of the actinoporin toxins sticholysin I and II (StnI and StnII) at 25 °C. Bilayer thickness was varied using dimonounsaturated phosphatidylcholine (PC) analogues [...]

Integration of Biorecognition Elements on PEDOT Platforms through Supramolecular Interactions

Publication year: 2017
Authors: Sappia L.D. 1,2, Piccinini E. 3, Marmisollé W. 3, Santilli N. 1, Maza E. 4, Moya S. 4, Battaglini F. 5, Madrid R.E. 1,2, Azzaroni O. 3
Published in: Advanced Materials Interfaces, 2017, 1700502
The rapidly emerging field of organic bioelectronics exploits the functional versatility of conducting polymers to transduce biological recognition events into electronic signals. For the majority of biosensors [...]

Investigation of graphene-on-metal substrates for SPR-based sensor using finite-difference time domain

Publication year: 2017
Authors: Said F. A. 1, Menon P. S. 1, Rajendran V. 2, Shaari S. 1, Majlis B. Y. 1
Published in: IET Nanobiotechnology, 2017, Vol. 11, Issue 8, p. 981 – 986
In this study, the authors investigated the effects of a single layer graphene as a coating layer on top of metal thin films such as silver, gold, aluminum and copper using finite-difference time domain method. [...]

“Click” access to multilayer functionalized Au surface: A terpyridine patterning example

Publication year: 2017
Authors: F.A. Martin a, D. Marconi a, S. Neamtu a, T. Radu a, M. Florescu b, R. Turcu a, C. Lar c, N.D. Hădade c, I. Grosu c, I. Turcu a
Published in: Materials Science and Engineering: C, 2017, Vol. 75, p. 1343–1350
This work is focused on self-assembled monolayers (SAMs) fabrication, using two types of Au surfaces, by subsequent attachment of different layers in order to develop [...]

Oligomerization Alters Binding Affinity Between Amyloid Beta and a Modulator of Peptide Aggregation

Publication year: 2017
Authors: Hilt S. 1, Rojalin T. 2, 3, Viitala T. 3, Koivuniemi A.3, Bunker A. 3, Wachsmann-Hogiu S. 2, 4, Kálai T. 5, Hideg K. 5, Yliperttula M. 3, 6, Voss J. C. 1
Published in: The Journal of Physical Chemistry C, 2017, Vol. 121 (43), p. 23974–23987
The soluble oligomeric form of the amyloid beta (Aβ) peptide is the major causative agent in the molecular pathogenesis of Alzheimer’s disease (AD). We have previously developed a pyrroline-nitroxyl fluorene compound (SLF) that blocks [...]

Immuno-biosensor for Detection of CD20-Positive Cells Using Surface Plasmon Resonance

Publication year: 2017
Authors: Shanehbandi D. 1,2, Majidi J. 1, Kazemi T. 1,2, Baradaran B. 1, Aghebati-Maleki L. 1,2, Fathi F. 2,3, Ezzati Nazhad Dolatabadi J. 3
Published in: Advanced Pharmaceutical Bulletin, 2017, Vol. 7 (2), p.188-194
Purpose: Surface plasmon resonance (SPR) sensing confers a real-time assessment of molecular interactions between biomolecules and their ligands. This approach is highly sensitive [...]

Bovine Serum Albumin Adsorption at a Silica Surface Explored by Simulation and Experiment

Publication year: 2017
Authors: Kubiak-Ossovska K. 1, Tokarczyk K. 2, Jachimska B. 2, Mulheran A.P. 1
Published in: Journal of Physical Chemistry B, 2017, Vol. 121 (16), p. 3975–3986
Molecular details of BSA adsorption on a silica surface are revealed by fully atomistic molecular dynamics (MD) simulations (with a 0.5 μs trajectory), supported by dynamic light scattering (DLS), zeta potential, [...]

Characterization of IFN-γ Detection and Electrochemical Proximity Assay by a Novel Multi-Parametric/Multimodal Spectroscopy Apparatus

Publication year: 2017
Authors: Zhou L., Chin B. A., Simonian A. L.*
Published in: ECS Transactions, 2017, Vol. 80, Issue 10, p. 1565-1570
Functional interfaces play a vital role in biosensing, which requires proper allocation, orientation, conformation, activities and stability to achieve high affinity and stability of the biomolecules. However, the characterization [...]

Layer-by-layer assemblies of highly connected polyelectrolyte capped-Pt nanoparticles for electrocatalysis of hydrogen evolution reaction

Publication year: 2017
Authors: Fenoy G.E. a, b, Maza E. a, c, Zelaya E. d, Marmisollé W.A. a, Azzaroni O. a
Published in: Applied Surface Science, 2017, Vol. 416, p. 24–32
Herein we present a simple one-step method to produce polyelectrolyte-capped Pt nanoparticles able to be assembled into layer-by-layer arrays [...]

Taste masking effect of chlorogenic acid (CGA) on bitter drugs evaluated by taste sensor and surface plasmon resonance on the basis of CGA-Drug interactions

Publication year: 2017
Authors: Shiraishi S.1, Haraguchi T., Nakamura S., Li D., Kojima H., Yoshida M., Uchida T.
Published in: Chemical and Pharmaceutical Bulletin, Vol. 65 (2017), No. 2, p. 127-13
The purpose of this study was to evaluate the taste-masking effects of chlorogenic acid (CGA) on bitter drugs using taste sensor measurements and surface plasmon resonance (SPR) analysis of CGA-drug interactions. [...]

Characterization of Covalently Bound Anti-Human Immunoglobulins on Self-Assembled Monolayer Modified Gold Electrodes

Publication year: 2017
Authors: Holzer B. 1, Manoli K. 1, Ditaranto N. 1,2, Macchia E. 1, Tiwari A. 1, Di Franco C. 3, Scamarcio G. 3,4, Palazzo G. 1,2, Torsi L. 1,2
Published in: Advanced Biosystems, 2017
Bioconjugated gold surfaces constitute interesting platforms for biosensing applications. The immobilization of antibodies such as anti-immunoglobulin G and M (anti-IgG and anti-IgM) [...]

Effect of Lipoxygenase Oxidation on Surface Deposition of Unsaturated Fatty Acids

Publication year: 2017
Authors: Tayeb A.H.1, Hubbe M.A.1, Zhang Y. 2 , Rojas O.J. 1,3
Published in: Langmuir, 2017, Vol. 33 (18), p. 4559–4566
We studied the interactions of lipid molecules (linoleic acid, glycerol trilinoleate and a complex mixture of wood extractives) with hydrophilic and hydrophobic surfaces (cellulose nanofibrils (CNFs) [...]

Endothelial cells' biophysical, biochemical, and chromosomal aberrancies in high ‐ glucose condition within the diabetic range

Publication year: 2017
Authors: Rezabakhsh A. 1,2, Nabat E. 2,3, Yousefi M. 4, Montazersaheb S. 2,5, Cheraghi O. 6, Mehdizadeh A. 7, Fathi F.8, Movassaghpour A.A. 9, Maleki-DIzaji N. 10, Rahbarghazi R. 2,11, Garjani A. 1,2,10
Published in: Cell Biochemistry & Function, 2017, p. 1-15
To date, many studies have been conducted to find out the underlying mechanisms of hyperglycemia-induced complications in diabetes mellitus, attributed to the cellular pathologies of different cells[...]

Graphene and graphene oxide for biosensing

Publication year: 2017
Authors: Kubesa O. 1, Horackova V. 2, Moravec Z. 2,3, Farka Z. 2, Skladal P. 1,2
Published in: Monatshefte für Chemie, 2017
Graphene-based nanomaterials attract large attention in electrochemistry due to their unique properties. Reliable method to modify electrodes by graphene is necessary to obtain desired improvement. In this work, [...]

Quantitative interpretation of PAMAM dendrimers adsorption on silica surface

Publication year: 2017
Authors: Tokarczyk K., Jachimska B
Published in: Journal of Colloid and Interface Science, 2017 Vol. 503, p. 86-94
Understanding the dendrimer-solid support interaction is of great importance for dendrimer-based drug delivery system design. The maximum surface coverage on a hydrophilic silica surface was determined using [...]

Kinetic and thermodynamic study of bovine serum albumin interaction with rifampicin using surface plasmon resonance and molecular docking methods

Publication year: 2017
Authors: Sharifi M. 1, Dolatabadi J.E. 2, Fathi F. 3, Rashidi M. 2, Jafari B. 4, Tajalli H. 1, Rashidi M.R. 2
Published in: Journal of Biomedical Optics, 2017, Vol. 22(3), p.
The interaction of bovine serum albumin (BSA) with various drugs, such as antibiotics, due to the importance of BSA in drug delivery has attracted increasing research attention at present. [...]

Ultrasensitive detection of nucleic acids and proteins using quartz crystal microbalance and surface plasmon resonance sensors based on target-triggering multiple signal amplification strategy

Publication year: 2017
Authors: Sun W. 1, Song W. 2, Guo X. 3, Wang Z. 1
Published in: Analytica Chimica Acta, 2017, Vol. 978, p. 42-47
In this study, quartz crystal microbalance (QCM) and surface plasmon resonance (SPR) sensors were combined with template enhanced hybridization processes (TEHP), rolling circle amplification (RCA) [...]