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Carboxyl-rich plasma polymer surfaces in surface plasmon resonance immunosensing

Publication year: 2018
Authors: Makhneva E. 1, 2, 6, Obrusnik A. 1, 2, 6, Farka Z. 3, Skladal P. 3, 4, Vandenbossche M. 5, Hegemann D. 5, Zajickova L. 1, 2
Published in: Japanese Journal of Applied Physics, 2018, Vol. 57, Number 1S, 01AG06
Stable carboxyl-rich plasma polymers (PPs) were deposited onto the gold surface of surface plasmon resonance (SPR) chips under conditions that were chosen based on lumped kinetic model results. Carboxyl-rich films are [...]

Tuning the Stiffness of Surfaces by Assembling Genetically Engineered Polypeptides with Tailored Amino Acid Sequence

Publication year: 2018
Authors: Costa R.R. 1,2, González-Pérez M. 3,4, Herrero-Gutiérrez M. 3,4, Pires R.A. 1,2,5, Alonso M. 3,4, Rodriguez-Cabello J.C. 3,4, Reis R.L. 1,2,5, Pashkuleva I. 1,2
Published in: Biomacromolecules, 2018, Vol. 19(8), p. 3401-3411
We introduce elastin-like recombinamers (ELRs) as polypeptides with precise amino acid positioning to generate polypeptide coatings with tunable rigidity. Two ELRs [...]

Stable, nanometer‐thick oxygen‐containing plasma polymer films suited for enhanced biosensing

Publication year: 2018
Authors: Hegeman D. 1, Indutnyi I. 2, Zajickova L. 3,4, Makhneva E. 3,4, Farka Z. 3, Ushenin Y. 2, Vandenbossche M. 1
Published in: Plasma Processes and Polymers, 2018, e1800090
Stable surface functionalization is required in many applications such as in biosensing. For this purpose, hydrocarbon‐based plasma polymer films (PPFs) were investigated by controlling cross‐linking [...]

Hydrazone crosslinked hyaluronan-based hydrogels for therapeutic delivery of adipose stem cells to treat corneal defects

Publication year: 2018
Authors: Koivusalo L. a, Karvinen J. e, Sorsa E. b, Jönkkäri I. c, Väliaho J. b, Kallio P. b, Ilmarinen T. a, Miettinen S. a, Skottman H. a, Kellomäki M. a, b
Published in: Materials Science and Engineering: C, Vol. 85, 2018, p. 68–78
Corneal blindness is a worldwide problem, plagued by insufficient amount of high-quality donor tissue. Cell therapy using human adipose stem cells (hASCs) has risen as an alternative [...]

Characterization of IFN-γ Detection and Electrochemical Proximity Assay by a Novel Multi-Parametric/Multimodal Spectroscopy Apparatus

Publication year: 2017
Authors: Zhou L., Chin B. A., Simonian A. L.*
Published in: ECS Transactions, 2017, Vol. 80, Issue 10, p. 1565-1570
Functional interfaces play a vital role in biosensing, which requires proper allocation, orientation, conformation, activities and stability to achieve high affinity and stability of the biomolecules. However, the characterization [...]

Layer-by-layer assemblies of highly connected polyelectrolyte capped-Pt nanoparticles for electrocatalysis of hydrogen evolution reaction

Publication year: 2017
Authors: Fenoy G.E. a, b, Maza E. a, c, Zelaya E. d, Marmisollé W.A. a, Azzaroni O. a
Published in: Applied Surface Science, 2017, Vol. 416, p. 24–32
Herein we present a simple one-step method to produce polyelectrolyte-capped Pt nanoparticles able to be assembled into layer-by-layer arrays [...]

Taste masking effect of chlorogenic acid (CGA) on bitter drugs evaluated by taste sensor and surface plasmon resonance on the basis of CGA-Drug interactions

Publication year: 2017
Authors: Shiraishi S.1, Haraguchi T., Nakamura S., Li D., Kojima H., Yoshida M., Uchida T.
Published in: Chemical and Pharmaceutical Bulletin, Vol. 65 (2017), No. 2, p. 127-13
The purpose of this study was to evaluate the taste-masking effects of chlorogenic acid (CGA) on bitter drugs using taste sensor measurements and surface plasmon resonance (SPR) analysis of CGA-drug interactions. [...]

Characterization of Covalently Bound Anti-Human Immunoglobulins on Self-Assembled Monolayer Modified Gold Electrodes

Publication year: 2017
Authors: Holzer B. 1, Manoli K. 1, Ditaranto N. 1,2, Macchia E. 1, Tiwari A. 1, Di Franco C. 3, Scamarcio G. 3,4, Palazzo G. 1,2, Torsi L. 1,2
Published in: Advanced Biosystems, 2017
Bioconjugated gold surfaces constitute interesting platforms for biosensing applications. The immobilization of antibodies such as anti-immunoglobulin G and M (anti-IgG and anti-IgM) [...]

Effect of Lipoxygenase Oxidation on Surface Deposition of Unsaturated Fatty Acids

Publication year: 2017
Authors: Tayeb A.H.1, Hubbe M.A.1, Zhang Y. 2 , Rojas O.J. 1,3
Published in: Langmuir, 2017, Vol. 33 (18), p. 4559–4566
We studied the interactions of lipid molecules (linoleic acid, glycerol trilinoleate and a complex mixture of wood extractives) with hydrophilic and hydrophobic surfaces (cellulose nanofibrils (CNFs) [...]

Endothelial cells' biophysical, biochemical, and chromosomal aberrancies in high ‐ glucose condition within the diabetic range

Publication year: 2017
Authors: Rezabakhsh A. 1,2, Nabat E. 2,3, Yousefi M. 4, Montazersaheb S. 2,5, Cheraghi O. 6, Mehdizadeh A. 7, Fathi F.8, Movassaghpour A.A. 9, Maleki-DIzaji N. 10, Rahbarghazi R. 2,11, Garjani A. 1,2,10
Published in: Cell Biochemistry & Function, 2017, p. 1-15
To date, many studies have been conducted to find out the underlying mechanisms of hyperglycemia-induced complications in diabetes mellitus, attributed to the cellular pathologies of different cells[...]

Graphene and graphene oxide for biosensing

Publication year: 2017
Authors: Kubesa O. 1, Horackova V. 2, Moravec Z. 2,3, Farka Z. 2, Skladal P. 1,2
Published in: Monatshefte für Chemie, 2017
Graphene-based nanomaterials attract large attention in electrochemistry due to their unique properties. Reliable method to modify electrodes by graphene is necessary to obtain desired improvement. In this work, [...]

Quantitative interpretation of PAMAM dendrimers adsorption on silica surface

Publication year: 2017
Authors: Tokarczyk K., Jachimska B
Published in: Journal of Colloid and Interface Science, 2017 Vol. 503, p. 86-94
Understanding the dendrimer-solid support interaction is of great importance for dendrimer-based drug delivery system design. The maximum surface coverage on a hydrophilic silica surface was determined using [...]

Kinetic and thermodynamic study of bovine serum albumin interaction with rifampicin using surface plasmon resonance and molecular docking methods

Publication year: 2017
Authors: Sharifi M. 1, Dolatabadi J.E. 2, Fathi F. 3, Rashidi M. 2, Jafari B. 4, Tajalli H. 1, Rashidi M.R. 2
Published in: Journal of Biomedical Optics, 2017, Vol. 22(3), p.
The interaction of bovine serum albumin (BSA) with various drugs, such as antibiotics, due to the importance of BSA in drug delivery has attracted increasing research attention at present. [...]

Ultrasensitive detection of nucleic acids and proteins using quartz crystal microbalance and surface plasmon resonance sensors based on target-triggering multiple signal amplification strategy

Publication year: 2017
Authors: Sun W. 1, Song W. 2, Guo X. 3, Wang Z. 1
Published in: Analytica Chimica Acta, 2017, Vol. 978, p. 42-47
In this study, quartz crystal microbalance (QCM) and surface plasmon resonance (SPR) sensors were combined with template enhanced hybridization processes (TEHP), rolling circle amplification (RCA) [...]

Lignin Films from Spruce, Eucalyptus, and Wheat Straw Studied with Electroacoustic and Optical Sensors: Effect of Composition and Electrostatic Screening on Enzyme Binding

Publication year: 2017
Authors: Pereira A. 1,2, Hoeger I.C. 2, Ferrer A. 2 , Rencoret J. 1, del Rio J.C. 1, Kruus K. 3§, Rahikainen J. 3, Kellock M. 3, Gutiérrez A. 1, Rojas O.J. 2,4
Published in: Biomacromolecules, 2017, Vol. 18 (4), p. 1322–1332
Lignins were isolated from spruce, wheat straw, and eucalyptus by using the milled wood lignin (MWL) method. Functional groups and compositional analyses were assessed [...]

Electrochemical Proximity Assay of Platelet-Derived Growth Factor through Combined Surface Plasmon Resonance, Electrochemistry, and Fluorescence Spectroscopy Approach

Publication year: 2017
Authors: Zhou L. a, Chin B.A. a, Simonian A.L. b
Published in: ECS Transactions, 2017, Vol. 77, Issue 11, p. 1809-1814
Platelet-derived growth factor (PDGF) is a potential cancer marker, which plays an important role in early detection of cancers. Due to its trace amounts in blood sample, it is difficult to be detected. [...]

New Approach for Thickness Determination of Solution-Deposited Graphene Thin Films

Publication year: 2017
Authors: Jussila H. 1,2, Albrow-Owen T. 1, Yang H. 2, Hu G. 1, Aksimsek S. 2,3, Granqvist N. 4, Lipsanen H. 2, Howe R.C.T. 1, Sun Z. 2, Hasan T. 1
Published in: ACS Omega, 2017, Vol. 2 (6), p. 2630–2638
Solution processing-based fabrication techniques such as liquid phase exfoliation may enable economically feasible utilization of graphene and related nanomaterials in real-world devices in the near future. [...]

Surface Plasmon Resonance for Measuring Exocytosis from Populations of PC12 Cells: Mechanisms of Signal Formation and Assessment of Analytical Capabilities

Publication year: 2017
Authors: Moreira B. 1, Tuoriniemi J. 1, Kouchak Pour N. 1, Mihalčíková L.1, Safina G. 1,2
Published in: Analytical Chemistry, 2017, Vol. 89 (5), p. 3069–3077
Because of cell to cell variation, it is difficult to obtain statistically significant data on the frequency of exocytosis events (Rexocytosis, t–1 m–2) with traditional single cell electrophysiological [...]

Interaction of industrially relevant cationic starches with cellulose

Publication year: 2017
Authors: Niegelhell K. a, b, Chemelli A. c, Hobisch J. d, Griesser T. e, Reiter H. b, f, Hirn U. a, f, Spirk S. a, b
Published in: Carbohydrate Polymers, Vol. 179, 2018, p. 290-296
Industrially relevant, commercially available cationic starches have been investigated towards their interaction capacity with cellulose thin films derived from trimethylsilyl cellulose (TMSC). The starches used in this study [...]

Breast Cancer Targeting Peptide Binds Keratin 1: A New Molecular Marker for Targeted Drug Delivery to Breast Cancer

Publication year: 2017
Authors: Soudy R. 1,2,5, Etayash H. 1, Bahadorani K.1, Lavasanifar A. 1,3, Kaur K. 1,4
Published in: Molecular Pharmaceutics, 2017, Vol. 14 (3), p. 593–604
The biomarkers or receptors expressed on cancer cells and the targeting ligands with high binding affinity for biomarkers play a key role in early detection and treatment of breast cancer. [...]