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Control of Protein Affinity of Bioactive Nanocellulose and Passivation Using Engineered Block and Random Copolymers

Publication year: 2016
Authors: Vuoriluoto M. 1, Orelma H. 1, Zhu B. 2, Johansson L.S. 1, Rojas O.J. 1
Published in: ACS Applied Materials & Interfaces, 2016, 2;8 (8), p: 5668-78
We passivated TEMPO-oxidized cellulose nanofibrils (TOCNF) toward human immunoglobulin G (hIgG) by modification with block and random copolymers of poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) and poly(oligo(ethylene glycol) methyl ether methacrylate) (POEGMA). [...]

Feasibility Study of the Permeability and Uptake of Mesoporous Silica Nanoparticles across the Blood-Brain Barrier

Publication year: 2016
Authors: Habib Baghirov 1,2,3,4, Didem Karaman 2,5, Tapani Viitala 6, Alain Duchanoy 2, Yan-Ru Lou 6, Veronika Mamaeva 1, Evgeny Pryazhnikov 7, Leonard Khiroug 7, Catharina de Lange Davies 4, Cecilia Sahlgren 1,3,8, Jessica M. Rosenholm 2,5
Published in: PLoS ONE 11(8): e0160705
Drug delivery into the brain is impeded by the blood-brain-barrier (BBB) that filters out the vast majority of drugs after systemic administration. In this work, we assessed the transport, uptake and cytotoxicity of promising drug nanocarriers, mesoporous silica nanoparticles (MSNs), [...]

Cationic and anionic polyelectrolyte complexes of xylan and chitosan. Interaction with lignocellulosic surfaces

Publication year: 2016
Authors: Mocchiutti P. 1, Schnell C.N. 2, Rossi G.D. 3, Peresin M.S. 4, Zanuttini M.A. 5, Galván M.V. 6
Published in: Carbohydrate Polymers, Vol. 150, p.89-98
Cationic (CatPECs) and anionic (AnPECs) polyelectrolyte complexes from xylan and chitosan were formed, characterized and adsorbed onto unbleached fibers for improving the papermaking properties.They were prepared [...]

Surfaces Mimicking Glycosaminoglycans Trigger Different Response of Stem Cells via Distinct Fibronectin Adsorption and Reorganization

Publication year: 2016
Authors: Araújo A.R. 1,2, Soares da Costa D. 1,2, Amorim S. 1.2, Reis R.L. 1,2, Pires R.A. 1,2 Pashkuleva I. 1,2
Published in: ACS Applied Materials & Interfaces, 2016, Vol. 8 (42), p. 28428–28436
We report on the utility of a platform created by self-assembled monolayers to investigate the influence of the degree of sulfation of glycosaminoglycans (GAGs) on their interactions with fibronectin (Fn) and the impact [...]

Enzymatic Precipitation Enhanced Surface Plasmon Resonance Immunosensor for the Detection of Salmonella in Powdered Milk

Publication year: 2016
Authors: Farka Z. 1, Juřík T. 1, 2, Pastucha M. 1, 2, Skládal P.1, 2
Published in: Analytical Chemistry, 2016, Vol. 88 (23), p. 11830–11836
Contamination of food by pathogenic bacteria has always been a serious threat for human health. The amount of food exports and imports has been increasing in recent years which requires precise food quality control [...]

Combining Surface Plasmon Resonance and Quartz Crystal Microbalance To Determine Hydration of Dendrimer Monolayers

Publication year: 2016
Authors: Barbara Jachimska and Karolina Tokarczyk
Published in: Journal of Physical Chemistry C
Polyelectrolytes are abundant in nature and crucial due to their versatility in biological systems. The controlled assembly of polyelectrolytes has potential applications in the formation of nanostructured and microstructured materials of desired structure and functionality. [...]

Optimization of lipodisk properties by modification of the extent and density of the PEG corona

Publication year: 2016
Authors: Zetterberg M.M. 1, Ahlgren S. 1, Agmo Hernández V. 1, Parveen N. 2, Edwards K. 1
Published in: Journal of Colloid and Interface Science, Vol. 484 (2016), p. 86–96
Lipodisks are nanosized flat, circular, phospholipid bilayers that are edge-stabilized by polyethylene glycol-conjugated lipids (PEG-lipids). Over the last decade, lipodisks stabilized [...]

SPR Biosensing MUA/Poly-L-lysine Platform for the Detection of 2,4-Dinitrophenol as Small Molecule Model System

Publication year: 2016
Authors: Millone M.A.D. 1, Ramirez E.A. 1, Chain C.Y. 1, Crivaro A. 2, Romanin D. 2, Rumbo M. 2, Docena G. 2, Cocco M.D. 3, Pedano M.L. 3, Fainstein A. 3, Montoya J. 4, Vela M.E. 1, Salvarezza R.C. 1
Published in: Journal of Nanomaterials, Vol. 2016, Article ID 5432656, 9 p.
Surface Plasmon Resonance assays are being developed as alternative biodetection methods for a great number of pesticides and toxins. These substances typically have low molecular weight, [...]

Real-Time Protein and Cell Binding Measurements on Hydroxyapatite Coatings

Publication year: 2016
Authors: A. M. Vilardell 1 , N. Cinca 1 , A. Jokinen 2, N. Garcia-Giralt 3, S. Dosta 1, I. G. Cano 1 and J. M. Guilemany 1
Published in: Journal of Functional Biomaterials, 2016, Vol. 7(3), p. 23
Although a lot of in vitro and in vivo assays have been performed during the last few decades years for hydroxyapatite bioactive coatings, there is a lack of exploitation of real-time in vitro interaction measurements. In the present work, real-time interactions for a plasma sprayed hydroxyapatite coating were measured by a Multi-Parametric Surface Plasmon Resonance (MP-SPR), [...]

Adsorption of Xyloglucan onto Cellulose Surfaces of Different Morphologies: An Entropy-Driven Process

Publication year: 2016
Authors: Tobias Benselfelt 1, Emily D. Cranston 2, Sedat Ondaral 3, Erik Johansson 4, Harry Brumer 5, Mark W. Rutland 6, and Lars Wågberg 1
Published in: Biomacromolecules, 2016, Vol. 17(9), p. 2801-11
The temperature-dependence of xyloglucan (XG) adsorption onto smooth cellulose model films regenerated from N-methylmorpholine N-oxide (NMMO) was investigated using surface plasmon resonance spectroscopy, and it was found that the adsorbed amount increased with increasing temperature. [...]

Real-Time Label-Free Monitoring of Nanoparticle Cell Uptake

Publication year: 2016
Authors: Suutari T. 1, Silen T. 1, S.en Karaman D. 2,3, Saari H. 1, Desai D. 2, Kerkelä E. 4, Laitinen S. 4, Hanzlikova M. 1, Rosenholm J.M. 2, Yliperttula M. 1,5, Viitala T. 6
Published in: Small
The surface plasmon resonance technique in combination with whole cell sensing is used for the first time for real-time label-free monitoring of nanoparticle cell uptake. The uptake kinetics of several types of nanoparticles [...]

Incorporation of gold nanoparticles into Langmuir-Blodgett films of polyaniline and montmorillonite for enhanced detection of metallic ions

Publication year: 2016
Authors: A. De Barros a, b, C.J.L. Constantino c, J.R.R. Bortoleto d, N.C. Da Cruz d, M. Ferreira b
Published in: Sensors and Actuators B: Chemical, Vol. 236, 2016, p. 408–417
We report on effects from incorporating gold nanoparticles (AuNPs) into Langmuir-Blodgett (LB) films of emeraldine salt polyaniline (PAni-ES) and organophilic montmorillonite clay (OMt). [...]

Topography effects in AFM force mapping experiments on xylan-decorated cellulose thin films

Publication year: 2016
Authors: Ganser Ch. 1,2,3, Niegelhell K. 4, Czibula C. 1,3, Chemelli A. 5, Teichert Ch. 1,3, Schennach R. 3,6, Spirk S. 4,7
Published in: International Journal of the Biology, Chemistry, Physics and Technology of Woo
Xylan-coated cellulose thin films has been investigated by means of atomic force microscopy (AFM) and force mapping experiments. The birch xylan deposition on the film was performed under control [...]

Effect of PEG–PDMAEMA Block Copolymer Architecture on Polyelectrolyte Complex Formation with Heparin

Publication year: 2016
Authors: Välimäki S. 1, Khakalo A. 2, Ora A. 1, Johansson L.-S. 2, Rojas O.J. 2, Kostiainen M.A. 1
Published in: Biomacromolecules, 2016, Vol. 17(9), p. 2891-900
Heparin is a naturally occurring polyelectrolyte consisting of a sulfated polysaccharide backbone. It is widely used as an anticoagulant during major surgical operations. However, the associated bleeding risks require rapid neutralization after the operation. [...]

Differential Effect of Membrane Composition on the Pore-Forming Ability of Four Different Sea Anemone Actinoporins

Publication year: 2016
Authors: García-Linares S. 1, 2, Rivera-de-Torre E. 1, Morante K. 3, Tsumoto K. 3, Caaveiro J.M.M. 3, Gavilanes J.G. 1, Slotte J.P. 2, Martínez-del-Pozo A. 1
Published in: Biochemistry, 2016, Vol. 55 (48), p. 6630–6641
Sea anemone actinoporins constitute a protein family of multigene pore-forming toxins (PFT). Equinatoxin II (EqtII), fragaceatoxin C (FraC), and sticholysins I and II (StnI and StnII, respectively), produced by three different sea anemone species, are the only actinoporins [...]

HRP-Mimicking DNAzyme-Catalyzed in Situ Generation of Polyaniline To Assist Signal Amplification for Ultrasensitive Surface Plasmon Resonance Biosensing

Publication year: 2016
Authors: Haiyin Li, Jiafu Chang, Ting Hou, Feng Li
Published in: Analytical Chemistry, 2017, Vol. 89 (1), p. 673–680
It is well-known that the horseradish peroxidase- (HRP-) mimicking DNAzyme, namely, hemin/G-quadruplex, can effectively catalyze the polymerization of aniline to form DNA-guided polyaniline. [...]

Determining Number Concentrations and Diameters of Polystyrene Particles by Measuring the Effective Refractive Index of Colloids Using Surface Plasmon Resonance

Publication year: 2016
Authors: Tuoriniemi J. 1, Moreira B. 1, Safina G. 1,2
Published in: Langmuir, 2016, Vol. 32 (41), p. 10632–10640
The capabilities of surface plasmon resonance (SPR) for characterization of colloidal particles were evaluated for 100, 300, and 460 nm nominal diameter polystyrene (PS) latexes. First the accuracy of measuring [...]

Enzymes as Biodevelopers for Nano- And Micropatterned Bicomponent Biopolymer Thin Films

Publication year: 2016
Authors: Niegelhell K. 1, Süßenbacher M. 1, Jammernegg K. 1, Ganner T. 2, Schwendenwein D. 3, Schwab H. 3, Stelzer F. 1, Plank H. 2, Spirk S. 1,4
Published in: Biomacromolecules, 2016, Vol. 17 (11), p. 3743–3749
The creation of nano- and micropatterned polymer films is a crucial step for innumerous applications in science and technology. However, there are several problems associated with environmental aspects concerning the polymer synthesis itself, cross-linkers to induce the patterns as well as toxic solvents [...]

Role of the Tryptophan Residues in the Specific Interaction of the Sea Anemone Stichodactyla helianthus’s Actinoporin Sticholysin II with Biological Membranes

Publication year: 2016
Authors: García-Linares S. 1, 2, Maula T. 2, Rivera-de-Torre E. 1, Gavilanes J.G. 1, Slotte J.P. 2, Martínez-del-Pozo A. 1
Published in: Biochemistry, 2016, Vol. 55 (46), p. 6406–6420
Actinoporins are pore-forming toxins from sea anemones. Upon interaction with sphingomyelin-containing bilayers, they become integral oligomeric membrane structures that form a pore. [...]

Using electrochemical surface plasmon resonance for in-situ kinetic investigations of solid electrolyte interphase formation in lithium ion battery

Publication year: 2016
Authors: Pradanawati S.A. a, Wang F.-M. a, b, Su Ch.-H. c
Published in: Journal of Power Sources, Vol. 330, 2016, p. 127–131
The solid electrolyte interphase (SEI) significantly affects the energy density and safety performance of lithium ion batteries. Previous studies have shown that conventional analyses cannot characterize the real-time [...]