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Graphene and graphene oxide for biosensing

Publication year: 2017
Authors: Kubesa O. 1, Horackova V. 2, Moravec Z. 2,3, Farka Z. 2, Skladal P. 1,2
Published in: Monatshefte für Chemie, 2017
Graphene-based nanomaterials attract large attention in electrochemistry due to their unique properties. Reliable method to modify electrodes by graphene is necessary to obtain desired improvement. In this work, [...]

Quantitative interpretation of PAMAM dendrimers adsorption on silica surface

Publication year: 2017
Authors: Tokarczyk K., Jachimska B
Published in: Journal of Colloid and Interface Science, 2017 Vol. 503, p. 86-94
Understanding the dendrimer-solid support interaction is of great importance for dendrimer-based drug delivery system design. The maximum surface coverage on a hydrophilic silica surface was determined using [...]

Binding Kinetics and Lateral Mobility of HSV-1 on End-Grafted Sulfated Glycosaminoglycans

Publication year: 2017
Authors: Peerboom N. 1, Block S. 2, Altgärde N. 1, Wahlsten O. 1, Möller S. 3, Schnabelrauch M. 3, Trybala E. 4, Bergström T. 4, Bally M. 5
Published in: Biophysics Journal, 2017, Vol. 113, Issue 6, p. 1223-1234
Many viruses, including herpes simplex (HSV), are recruited to their host cells via interaction between their envelope glycoproteins and cell-surface glycosaminoglycans (GAGs). This initial attachment [...]

How Bound and Free Fatty Acids in Cellulose Films Impact Nonspecific Protein Adsorption

Publication year: 2017
Authors: Niegelhell K. a, Suessenbacher M. b, Sattelkow J. c, Plank H. c, Wang Y. d, Zhang K. d, Spirk S. a
Published in: Biomacromolecules, 2017, Vol. 18 (12), p. 4224–4231
The effect of fatty acids and fatty acid esters to impair nonspecific protein adsorption on cellulose thin films is investigated. Thin films are prepared by blending trimethylsilyl cellulose solutions with either cellulose stearoyl ester [...]

Differential Effect of Bilayer Thickness on Sticholysin Activity

Publication year: 2017
Authors: Palacios-Ortega J. 1, 2, García-Linares S. 1, 2, Rivera-de-Torre E. 1, Gavilanes J.G. 1, Martínez-del-Pozo A. 1, Slotte J.P. 2
Published in: Langmuir, 2017, Vol. 33 (41), p. 11018–11027
In this study, we examined the influence of bilayer thickness on the activity of the actinoporin toxins sticholysin I and II (StnI and StnII) at 25 °C. Bilayer thickness was varied using dimonounsaturated phosphatidylcholine (PC) analogues [...]

Ultrasensitive detection of nucleic acids and proteins using quartz crystal microbalance and surface plasmon resonance sensors based on target-triggering multiple signal amplification strategy

Publication year: 2017
Authors: Sun W. 1, Song W. 2, Guo X. 3, Wang Z. 1
Published in: Analytica Chimica Acta, 2017, Vol. 978, p. 42-47
In this study, quartz crystal microbalance (QCM) and surface plasmon resonance (SPR) sensors were combined with template enhanced hybridization processes (TEHP), rolling circle amplification (RCA) [...]

Lignin Films from Spruce, Eucalyptus, and Wheat Straw Studied with Electroacoustic and Optical Sensors: Effect of Composition and Electrostatic Screening on Enzyme Binding

Publication year: 2017
Authors: Pereira A. 1,2, Hoeger I.C. 2, Ferrer A. 2 , Rencoret J. 1, del Rio J.C. 1, Kruus K. 3§, Rahikainen J. 3, Kellock M. 3, Gutiérrez A. 1, Rojas O.J. 2,4
Published in: Biomacromolecules, 2017, Vol. 18 (4), p. 1322–1332
Lignins were isolated from spruce, wheat straw, and eucalyptus by using the milled wood lignin (MWL) method. Functional groups and compositional analyses were assessed [...]

Effect of Ionic Strength and Surface Charge Density on the Kinetics of Cellulose Nanocrystal Thin Film Swelling

Publication year: 2017
Authors: Reid M.S. 1, Kedzior S.A. 1, Villalobos M. 2, Cranston E.D. 1
Published in: Langmuir, 2017, Vol. 33 (30), p. 7403–7411
This work explores cellulose nanocrystal (CNC) thin films (<50 nm) and particle–particle interactions by investigating film swelling in aqueous solutions with varying ionic strength [...]

Protein Adsorption Tailors the Surface Energies and Compatibility between Polylactide and Cellulose Nanofibrils

Publication year: 2017
Authors: A. Khakalo 1, I. Filpponen 1,2, O.J. Rojas 1,3
Published in: Biomacromolecules, 2017, Vol. 18 (4), p. 1426–1433
The state of dispersion and the interactions between a polymer and a filler in a nanocomposite crucially define its properties and performance.The affinity of polylactide (PLA) [...]

Oligomerization Alters Binding Affinity Between Amyloid Beta and a Modulator of Peptide Aggregation

Publication year: 2017
Authors: Hilt S. 1, Rojalin T. 2, 3, Viitala T. 3, Koivuniemi A.3, Bunker A. 3, Wachsmann-Hogiu S. 2, 4, Kálai T. 5, Hideg K. 5, Yliperttula M. 3, 6, Voss J. C. 1
Published in: The Journal of Physical Chemistry C, 2017, Vol. 121 (43), p. 23974–23987
The soluble oligomeric form of the amyloid beta (Aβ) peptide is the major causative agent in the molecular pathogenesis of Alzheimer’s disease (AD). We have previously developed a pyrroline-nitroxyl fluorene compound (SLF) that blocks [...]

Electrochemical Proximity Assay of Platelet-Derived Growth Factor through Combined Surface Plasmon Resonance, Electrochemistry, and Fluorescence Spectroscopy Approach

Publication year: 2017
Authors: Zhou L. a, Chin B.A. a, Simonian A.L. b
Published in: ECS Transactions, 2017, Vol. 77, Issue 11, p. 1809-1814
Platelet-derived growth factor (PDGF) is a potential cancer marker, which plays an important role in early detection of cancers. Due to its trace amounts in blood sample, it is difficult to be detected. [...]

New Approach for Thickness Determination of Solution-Deposited Graphene Thin Films

Publication year: 2017
Authors: Jussila H. 1,2, Albrow-Owen T. 1, Yang H. 2, Hu G. 1, Aksimsek S. 2,3, Granqvist N. 4, Lipsanen H. 2, Howe R.C.T. 1, Sun Z. 2, Hasan T. 1
Published in: ACS Omega, 2017, Vol. 2 (6), p. 2630–2638
Solution processing-based fabrication techniques such as liquid phase exfoliation may enable economically feasible utilization of graphene and related nanomaterials in real-world devices in the near future. [...]

Glycotriazole-peptides derived from the peptide HSP1: synergistic effect of triazole and saccharide rings on the antifungal activity

Publication year: 2017
Authors: Junior E.F.C. 1, Guimarães C.F.R.C. 2, Franco L.L. 3, Alves R.J. 3, Kato K.C. 4, Martins H.R. 4, de Souza Filho J.D. 2, Bemquerer M.P. 5, Munhoz V.H.O. 6, Resende J.M. 2, Verly R.M. 7
Published in: Amino Acids, 2017, Vol. 49(8), p. 1389-1400
This work proposes a strategy that uses solid-phase peptide synthesis associated with copper(I)-catalyzed azide alkyne cycloaddition reaction to promote the glycosylation of an antimicrobial peptide (HSP1) [...]

Interaction of industrially relevant cationic starches with cellulose

Publication year: 2017
Authors: Niegelhell K. a, b, Chemelli A. c, Hobisch J. d, Griesser T. e, Reiter H. b, f, Hirn U. a, f, Spirk S. a, b
Published in: Carbohydrate Polymers, Vol. 179, 2018, p. 290-296
Industrially relevant, commercially available cationic starches have been investigated towards their interaction capacity with cellulose thin films derived from trimethylsilyl cellulose (TMSC). The starches used in this study [...]

Label-free evaluation of carbon nanoparticles in Layer-by-Layer self-assembled enzyme-based biosensors

Publication year: 2017
Authors: David M. a, Florescu M. b, Barsan M. M. c, Brett M.A.C. c
Published in: Procedia Technology, Vo. 27, 2017, p. 304-305
The immobilization of biomolecules and the enhancement of the electron transfer are important factors regarding the performances of the enzyme-based biosensors. Layer-by-layer (LbL) strategies can be effectively used [...]

The effect of chemical additives on the strength, stiffness and elongation potential of paper

Publication year: 2017
Authors: Strand A. c, Khakalo A. a, Kouko J. b, Oksanen A. b, Ketola A. b, Salminen K. b, Rojas O. a, Retulainen E. b, Sundberg A. c
Published in: Nordic Pulp & Paper Research Journal, 2017, Vol. 32 No. 3, p. 324-335
The effects of wet-end additions of cationic starches and/or carboxymethyl cellulose (CMC) on paper properties was determined by papermaking trials. The aim of this study was to mitigate the distinctive decrease in strength [...]

Role of the Tryptophan Residues in the Specific Interaction of the Sea Anemone Stichodactyla helianthus’s Actinoporin Sticholysin II with Biological Membranes

Publication year: 2016
Authors: García-Linares S. 1, 2, Maula T. 2, Rivera-de-Torre E. 1, Gavilanes J.G. 1, Slotte J.P. 2, Martínez-del-Pozo A. 1
Published in: Biochemistry, 2016, Vol. 55 (46), p. 6406–6420
Actinoporins are pore-forming toxins from sea anemones. Upon interaction with sphingomyelin-containing bilayers, they become integral oligomeric membrane structures that form a pore. [...]

Using electrochemical surface plasmon resonance for in-situ kinetic investigations of solid electrolyte interphase formation in lithium ion battery

Publication year: 2016
Authors: Pradanawati S.A. a, Wang F.-M. a, b, Su Ch.-H. c
Published in: Journal of Power Sources, Vol. 330, 2016, p. 127–131
The solid electrolyte interphase (SEI) significantly affects the energy density and safety performance of lithium ion batteries. Previous studies have shown that conventional analyses cannot characterize the real-time [...]

Lignocellulosic Materials and their Interactions with Proteins and Surface Active Molecules

Publication year: 2016
Authors: Fritz C.
Published in: Doctoral dissertation, North Carolina State University
Lignocellulosic biomass is a highly valuable resource for the development of value-added biobased chemicals and other materials. However, the efficient utilization of this biomass regards on understanding the different interactions [...]

Phenylboronic-Acid-Based Polymeric Micelles for Mucoadhesive Anterior Segment Ocular Drug Delivery

Publication year: 2016
Authors: Prosperi-Porta G. 1, Kedzior S. 2, Muirhead B. 1, Sheardown H. 1,2
Published in: Biomacromolecules, 2016, Vol. 17(4), p. 1449-57
Topical drug delivery to the front of the eye is extremely inefficient due to effective natural protection mechanisms such as precorneal tear turnover and the relative impermeability of the cornea and sclera tissues. This causes low ocular drug bioavailability, requiring large frequent doses that result in high systemic exposure and side effects.[...]