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Salt-Induced Control of the Grafting Density in Poly(ethylene glycol) Brush Layers by a Grafting-to Approach

Publication year: 2018
Authors: Ortiz R. 1, Olsen S. 2, Thormann E. 1
Published in: Langmuir, 2018, Vol. 34(15), p. 4455-4464
In this work, a method to obtain control of the grafting density during the formation of polymer brush layers by the grafting-to method of thiolated poly(ethylene glycol) onto gold is presented. The grafting density [...]

On the Importance of Controlling Film Architecture in Detecting Prostate Specific Antigen

Publication year: 2018
Authors: Graça J. S. a, Miyazaki C. M. a, Shimizu F. M. b, Volpati D. c, Mejía-Salazar J. R. b, Oliveira O.N. Jr. b, Ferreira M. a
Published in: Applied Surface Science, 2018, Vol. 434, p. 1175-1182
Immunosensors made with nanostructured films are promising for detecting cancer biomarkers, even at early stages of the disease, but this requires control of film architecture to preserve [...]

A DNA–nanoparticle actuator enabling optical monitoring of nanoscale movements induced by an electric field

Publication year: 2018
Authors: Tapio K. a, Shao D. a, Auer S. b, Tuppurainen J. c, Ahlskog M. a, Hytönen V.P. b, Toppari J.J. a*
Published in: Nanoscale, 2018, Vol. 10, p. 19297-19309
Merging biological and non-biological matter to fabricate nanoscale assemblies with controllable motion and function is of great interest due to its potential application, for example, in diagnostics and biosensing. [...]

Spin coated chitin films for biosensors and its analysis are dependent on chitin-surface interactions

Publication year: 2018
Authors: Casteleijn M. G. a, Richardson D. a, Parkkila P. a, Granqvist N. b, Urtti A. a, c, Viitala T. a
Published in: Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2018, Vol. 539, p. 261-272
Chitin, abundant in nature, is a renewable resource with many possible applications in bioengineering. Biosensors, capable of label-free and in-line evaluation, play an important role in the investigation of [...]

Quantitative Analysis of Thickness and pH Actuation of Weak Polyelectrolyte Brushes

Publication year: 2018
Authors: Ferrand-Drake del Castillo G., Emilsson G., Dahlin A.
Published in: The Journal of Physical Chemistry C, 2018, Issue 122 (48), p. 27516–27527
Polymer brushes are widely used as surface coatings for various inert, functional, or responsive interfaces. If the polymer can alter its protonation state (a polyelectrolyte (PE)), the brush can switch [...]

Angiogenic and Restorative Abilities of Human Mesenchymal Stem Cells Were Reduced Following Treatment With Serum From Diabetes Mellitus Type 2 Patients

Publication year: 2017
Authors: Rezaie J. 1, Mehranjani M.S. 1, Rahbarghazi R. 2,3, Shariatzadeh M.A. 1
Published in: Journal of Cellular Biochemistry, 2017, 9999, p. 1-12
This experiment investigated the impact of serum from patients with type 2 diabetes mellitus on the angiogenic behavior of human mesenchymal stem cells in vitro. Changes in the level [...]

Ionic strength-controlled hybridization and stability of hybrids of KRAS DNA single-nucleotides: A surface plasmon resonance study

Publication year: 2017
Authors: Giamblanco N. 1, Petralia S. 2, Conoci S. 3, Messineo C. 4, Marletta G. 4
Published in: Colloids and Surfaces B: Biointerfaces, 2017, Vol. 158, p. 41-46
The discrimination of a fully matched, unlabeled KRAS wild-type (WT) (C-G) target sample with respect to three of the most frequent KRAS codon mutations (G12 S (C-A), G12 R (C-C), G12C (C-T)) was investigated using an [...]

New Approach for Thickness Determination of Solution-Deposited Graphene Thin Films

Publication year: 2017
Authors: Jussila H. 1,2, Albrow-Owen T. 1, Yang H. 2, Hu G. 1, Aksimsek S. 2,3, Granqvist N. 4, Lipsanen H. 2, Howe R.C.T. 1, Sun Z. 2, Hasan T. 1
Published in: ACS Omega, 2017, Vol. 2 (6), p. 2630–2638
Solution processing-based fabrication techniques such as liquid phase exfoliation may enable economically feasible utilization of graphene and related nanomaterials in real-world devices in the near future. [...]

Glycotriazole-peptides derived from the peptide HSP1: synergistic effect of triazole and saccharide rings on the antifungal activity

Publication year: 2017
Authors: Junior E.F.C. 1, Guimarães C.F.R.C. 2, Franco L.L. 3, Alves R.J. 3, Kato K.C. 4, Martins H.R. 4, de Souza Filho J.D. 2, Bemquerer M.P. 5, Munhoz V.H.O. 6, Resende J.M. 2, Verly R.M. 7
Published in: Amino Acids, 2017, Vol. 49(8), p. 1389-1400
This work proposes a strategy that uses solid-phase peptide synthesis associated with copper(I)-catalyzed azide alkyne cycloaddition reaction to promote the glycosylation of an antimicrobial peptide (HSP1) [...]

Protein Adsorption Tailors the Surface Energies and Compatibility between Polylactide and Cellulose Nanofibrils

Publication year: 2017
Authors: A. Khakalo 1, I. Filpponen 1,2, O.J. Rojas 1,3
Published in: Biomacromolecules, 2017, Vol. 18 (4), p. 1426–1433
The state of dispersion and the interactions between a polymer and a filler in a nanocomposite crucially define its properties and performance.The affinity of polylactide (PLA) [...]

Surface plasmon resonance and molecular docking studies of bovine serum albumin interaction with neomycin: kinetic and thermodynamic analysis

Publication year: 2017
Authors: Sharifi M. 1, Dolatabadi J.E.N. 2, Fathi F. 2,3, Zakariazadeh M. 4, Barzegar A. 4, Rashidi M. 2, Tajalli H. 1, Rashidi M.-R. 2
Published in: BioImpacts, 2017, Vol. 7(2), p. 91–97
Introduction: The interactions between biomacromolecules such as serum albumin (SA) and various drugs have attracted increasing research attention in recent years. [...]

Detection of transferrin by using a surface plasmon resonance sensor functionalized with a boronic acid monolayer

Publication year: 2017
Authors: Yanchao Mayang 1,2, Xiwen He 1,2, Langxing Chen 1,2, Yukui Zhang 1,2,3
Published in: Microchimica Acta, 2017, Vol. 184 (8), p. 2749–2757
A surface plasmon resonance sensor whose surface has been modified with boronic acid groups was developed in order to bind and detect transferrin. 4-Mercaptophenylboronic acid (4-MPBA) was utilized [...]

Interaction of industrially relevant cationic starches with cellulose

Publication year: 2017
Authors: Niegelhell K. a, b, Chemelli A. c, Hobisch J. d, Griesser T. e, Reiter H. b, f, Hirn U. a, f, Spirk S. a, b
Published in: Carbohydrate Polymers, Vol. 179, 2018, p. 290-296
Industrially relevant, commercially available cationic starches have been investigated towards their interaction capacity with cellulose thin films derived from trimethylsilyl cellulose (TMSC). The starches used in this study [...]

Interaction of Solid Lipid Nanoparticles and Specific Proteins of the Corona Studied by Surface Plasmon Resonance

Publication year: 2017
Authors: Mauricio E. Di Ianni 1, Germán A. Islan 2, Cecilia Y. Chain 3, Guillermo R. Castro 2, Alan Talevi 1, María E. Vela 3
Published in: Journal of Nanomaterials, Vol. 2017, 11 pages
The applications of pharmaceutical and medical nanosystems are among the most intensively investigated fields in nanotechnology. A relevant point to be considered in the design and development [...]

Integration of Biorecognition Elements on PEDOT Platforms through Supramolecular Interactions

Publication year: 2017
Authors: Sappia L.D. 1,2, Piccinini E. 3, Marmisollé W. 3, Santilli N. 1, Maza E. 4, Moya S. 4, Battaglini F. 5, Madrid R.E. 1,2, Azzaroni O. 3
Published in: Advanced Materials Interfaces, 2017, 1700502
The rapidly emerging field of organic bioelectronics exploits the functional versatility of conducting polymers to transduce biological recognition events into electronic signals. For the majority of biosensors [...]

Investigation of graphene-on-metal substrates for SPR-based sensor using finite-difference time domain

Publication year: 2017
Authors: Said F. A. 1, Menon P. S. 1, Rajendran V. 2, Shaari S. 1, Majlis B. Y. 1
Published in: IET Nanobiotechnology, 2017, Vol. 11, Issue 8, p. 981 – 986
In this study, the authors investigated the effects of a single layer graphene as a coating layer on top of metal thin films such as silver, gold, aluminum and copper using finite-difference time domain method. [...]

The effect of chemical additives on the strength, stiffness and elongation potential of paper

Publication year: 2017
Authors: Strand A. c, Khakalo A. a, Kouko J. b, Oksanen A. b, Ketola A. b, Salminen K. b, Rojas O. a, Retulainen E. b, Sundberg A. c
Published in: Nordic Pulp & Paper Research Journal, 2017, Vol. 32 No. 3, p. 324-335
The effects of wet-end additions of cationic starches and/or carboxymethyl cellulose (CMC) on paper properties was determined by papermaking trials. The aim of this study was to mitigate the distinctive decrease in strength [...]

Differential Effect of Bilayer Thickness on Sticholysin Activity

Publication year: 2017
Authors: Palacios-Ortega J. 1, 2, García-Linares S. 1, 2, Rivera-de-Torre E. 1, Gavilanes J.G. 1, Martínez-del-Pozo A. 1, Slotte J.P. 2
Published in: Langmuir, 2017, Vol. 33 (41), p. 11018–11027
In this study, we examined the influence of bilayer thickness on the activity of the actinoporin toxins sticholysin I and II (StnI and StnII) at 25 °C. Bilayer thickness was varied using dimonounsaturated phosphatidylcholine (PC) analogues [...]

Immuno-biosensor for Detection of CD20-Positive Cells Using Surface Plasmon Resonance

Publication year: 2017
Authors: Shanehbandi D. 1,2, Majidi J. 1, Kazemi T. 1,2, Baradaran B. 1, Aghebati-Maleki L. 1,2, Fathi F. 2,3, Ezzati Nazhad Dolatabadi J. 3
Published in: Advanced Pharmaceutical Bulletin, 2017, Vol. 7 (2), p.188-194
Purpose: Surface plasmon resonance (SPR) sensing confers a real-time assessment of molecular interactions between biomolecules and their ligands. This approach is highly sensitive [...]

Oligomerization Alters Binding Affinity Between Amyloid Beta and a Modulator of Peptide Aggregation

Publication year: 2017
Authors: Hilt S. 1, Rojalin T. 2, 3, Viitala T. 3, Koivuniemi A.3, Bunker A. 3, Wachsmann-Hogiu S. 2, 4, Kálai T. 5, Hideg K. 5, Yliperttula M. 3, 6, Voss J. C. 1
Published in: The Journal of Physical Chemistry C, 2017, Vol. 121 (43), p. 23974–23987
The soluble oligomeric form of the amyloid beta (Aβ) peptide is the major causative agent in the molecular pathogenesis of Alzheimer’s disease (AD). We have previously developed a pyrroline-nitroxyl fluorene compound (SLF) that blocks [...]