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Electrochemical Proximity Assay of Platelet-Derived Growth Factor through Combined Surface Plasmon Resonance, Electrochemistry, and Fluorescence Spectroscopy Approach

Publication year: 2017
Authors: Lang Zhou a, Bryan A Chin a, Aleksandr L. Simonian b
Published in: ECS Translations, 2017, Vol. 77 (11), p. 1809-1814
Platelet-derived growth factor (PDGF) is a potential cancer marker, which plays an important role in early detection of cancers. Due to its trace amounts in blood sample, it is difficult to be detected. [...]

Ultrasensitive detection of nucleic acids and proteins using quartz crystal microbalance and surface plasmon resonance sensors based on target-triggering multiple signal amplification strategy

Publication year: 2017
Authors: Sun W. 1, Song W. 2, Guo X. 3, Wang Z. 1
Published in: Analytica Chimica Acta, 2017, Vol. 978, p. 42-47
In this study, quartz crystal microbalance (QCM) and surface plasmon resonance (SPR) sensors were combined with template enhanced hybridization processes (TEHP), rolling circle amplification (RCA) [...]

Graphene and graphene oxide for biosensing

Publication year: 2017
Authors: Kubesa O. 1, Horackova V. 2, Moravec Z. 2,3, Farka Z. 2, Skladal P. 1,2
Published in: Monatshefte für Chemie, 2017
Graphene-based nanomaterials attract large attention in electrochemistry due to their unique properties. Reliable method to modify electrodes by graphene is necessary to obtain desired improvement. In this work, [...]

Binding Kinetics and Lateral Mobility of HSV-1 on End-Grafted Sulfated Glycosaminoglycans

Publication year: 2017
Authors: Peerboom N. 1, Block S. 2, Altgärde N. 1, Wahlsten O. 1, Möller S. 3, Schnabelrauch M. 3, Trybala E. 4, Bergström T. 4, Bally M. 5
Published in: Biophysics Journal, 2017
Many viruses, including herpes simplex (HSV), are recruited to their host cells via interaction between their envelope glycoproteins and cell-surface glycosaminoglycans (GAGs). This initial attachment [...]

Effect of Molecular Architecture on Cell Interactions and Stealth Properties of PEG

Publication year: 2017
Authors: Imran Ozer †‡§, Aysel Tomak ∥, Hadi M. Zareie ∥⊥, Yusuf Baran #○, Volga Bulmus †‡
Published in: Biomacromolecules, 2017
PEGylation, covalent attachment of PEG to therapeutic biomolecules, in which suboptimal pharmacokinetic profiles limiting their therapeutic utility are of concern, is a widely applied technology. However, this technology [...]

Characterization of Covalently Bound Anti-Human Immunoglobulins on Self-Assembled Monolayer Modified Gold Electrodes

Publication year: 2017
Authors: Holzer B. 1, Manoli K. 1, Ditaranto N. 1,2, Macchia E. 1, Tiwari A. 1, Di Franco C. 3, Scamarcio G. 3,4, Palazzo G. 1,2, Torsi L. 1,2
Published in: Advanced Biosystems, 2017
Bioconjugated gold surfaces constitute interesting platforms for biosensing applications. The immobilization of antibodies such as anti-immunoglobulin G and M (anti-IgG and anti-IgM) [...]

Interaction of Solid Lipid Nanoparticles and Specific Proteins of the Corona Studied by Surface Plasmon Resonance

Publication year: 2017
Authors: Mauricio E. Di Ianni 1, Germán A. Islan 2, Cecilia Y. Chain 3, Guillermo R. Castro 2, Alan Talevi 1, María E. Vela 3
Published in: Journal of Nanomaterials, Vol. 2017, 11 pages
The applications of pharmaceutical and medical nanosystems are among the most intensively investigated fields in nanotechnology. A relevant point to be considered in the design and development [...]

Development of a surface plasmon resonance sensor for coupling to capillary electrophoresis allowing affinity assessment of protein mixture components

Publication year: 2017
Authors: Domínguez-Vega E. a, Haselberg R. a, van Iperen D. b, Kool J. a, Somsen G.W. a, de Jong G.J. c
Published in: Sensors and Actuators B: Chemical, 2017, Vol. 254, p. 1040-1047
Surface plasmon resonance (SPR) currently is the major platform to study protein–protein interactions, but it lacks the selectivity o distinguish between binding components within one sample. [...]

Surface plasmon resonance and molecular docking studies of bovine serum albumin interaction with neomycin: kinetic and thermodynamic analysis

Publication year: 2017
Authors: Sharifi M. 1, Dolatabadi J.E.N. 2, Fathi F. 2,3, Zakariazadeh M. 4, Barzegar A. 4, Rashidi M. 2, Tajalli H. 1, Rashidi M.-R. 2
Published in: BioImpacts, 2017, Vol. 7(2), p. 91–97
Introduction: The interactions between biomacromolecules such as serum albumin (SA) and various drugs have attracted increasing research attention in recent years. [...]

Glycotriazole-peptides derived from the peptide HSP1: synergistic effect of triazole and saccharide rings on the antifungal activity

Publication year: 2017
Authors: Junior E.F.C. 1, Guimarães C.F.R.C. 2, Franco L.L. 3, Alves R.J. 3, Kato K.C. 4, Martins H.R. 4, de Souza Filho J.D. 2, Bemquerer M.P. 5, Munhoz V.H.O. 6, Resende J.M. 2, Verly R.M. 7
Published in: Amino Acids, 2017, Vol. 49(8), p. 1389-1400
This work proposes a strategy that uses solid-phase peptide synthesis associated with copper(I)-catalyzed azide alkyne cycloaddition reaction to promote the glycosylation of an antimicrobial peptide (HSP1) [...]

Immuno-biosensor for Detection of CD20-Positive Cells Using Surface Plasmon Resonance

Publication year: 2017
Authors: Shanehbandi D. 1,2, Majidi J. 1, Kazemi T. 1,2, Baradaran B. 1, Aghebati-Maleki L. 1,2, Fathi F. 2,3, Ezzati Nazhad Dolatabadi J. 3
Published in: Advanced Pharmaceutical Bulletin, 2017, Vol. 7 (2), p.188-194
Purpose: Surface plasmon resonance (SPR) sensing confers a real-time assessment of molecular interactions between biomolecules and their ligands. This approach is highly sensitive [...]

Effect of Ionic Strength and Surface Charge Density on the Kinetics of Cellulose Nanocrystal Thin Film Swelling

Publication year: 2017
Authors: Michael S. Reid † , Stephanie A. Kedzior †, Marco Villalobos ‡, Emily D. Cranston*†
Published in: Langmuir, 2017, Vol. 33 (30), p. 7403–7411
This work explores cellulose nanocrystal (CNC) thin films (<50 nm) and particle–particle interactions by investigating film swelling in aqueous solutions with varying ionic strength [...]

Integration of Biorecognition Elements on PEDOT Platforms through Supramolecular Interactions

Publication year: 2017
Authors: Sappia L.D. 1,2, Piccinini E. 3, Marmisollé W. 3, Santilli N. 1, Maza E. 4, Moya S. 4, Battaglini F. 5, Madrid R.E. 1,2, Azzaroni O. 3
Published in: Advanced Materials Interfaces, 2017, 1700502
The rapidly emerging field of organic bioelectronics exploits the functional versatility of conducting polymers to transduce biological recognition events into electronic signals. For the majority of biosensors [...]

Detection of transferrin by using a surface plasmon resonance sensor functionalized with a boronic acid monolayer

Publication year: 2017
Authors: Yanchao Mayang 1,2, Xiwen He 1,2, Langxing Chen 1,2, Yukui Zhang 1,2,3
Published in: Microchimica Acta, 2017, Vol. 184 (8), p. 2749–2757
A surface plasmon resonance sensor whose surface has been modified with boronic acid groups was developed in order to bind and detect transferrin. 4-Mercaptophenylboronic acid (4-MPBA) was utilized [...]

Angiogenic and Restorative Abilities of Human Mesenchymal Stem Cells Were Reduced Following Treatment With Serum From Diabetes Mellitus Type 2 Patients

Publication year: 2017
Authors: Rezaie J. 1, Mehranjani M.S. 1, Rahbarghazi R. 2,3, Shariatzadeh M.A. 1
Published in: Journal of Cellular Biochemistry, 2017, 9999, p. 1-12
This experiment investigated the impact of serum from patients with type 2 diabetes mellitus on the angiogenic behavior of human mesenchymal stem cells in vitro. Changes in the level [...]

Ionic strength-controlled hybridization and stability of hybrids of KRAS DNA single-nucleotides: A surface plasmon resonance study

Publication year: 2017
Authors: Giamblanco N. 1, Petralia S. 2, Conoci S. 3, Messineo C. 4, Marletta G. 4
Published in: Colloids and Surfaces B: Biointerfaces, 2017, Vol. 158, p. 41-46
The discrimination of a fully matched, unlabeled KRAS wild-type (WT) (C-G) target sample with respect to three of the most frequent KRAS codon mutations (G12 S (C-A), G12 R (C-C), G12C (C-T)) was investigated using an [...]

New Approach for Thickness Determination of Solution-Deposited Graphene Thin Films

Publication year: 2017
Authors: Henri Jussila †‡, Tom Albrow-Owen †, He Yang ‡, Guohua Hu †, Sinan Aksimsek §‡, Niko Granqvist ∥, Harri Lipsanen ‡, Richard C. T. Howe †, Zhipei Sun ‡, Tawfique Hasan †
Published in: ACS Omega, 2017, Vol. 2 (6), p. 2630–2638
Solution processing-based fabrication techniques such as liquid phase exfoliation may enable economically feasible utilization of graphene and related nanomaterials in real-world devices in the near future. [...]

Early-stage detection of VE-cadherin during endothelial differentiation of human mesenchymal stem cells using SPR biosensor

Publication year: 2017
Authors: Fathi F. 1, Rezabakhsh A. 2, Rahbarghazi R. 3, Rashidi M.R. 4
Published in: Biosensors and Bioelectronics, 2017, Vol. 96, p. 358-366
Surface plasmon resonance (SPR) biosensors are most commonly applied for real-time dynamic analysis and measurement of interactions in bio-molecular studies and cell-surface analysis without the need for labeling processes. [...]

Detachment of Membrane Bound Virions by Competitive Ligand Binding Induced Receptor Depletion

Publication year: 2017
Authors: Parveen N. 1, Block S. 1, Zhdanov V.P. 1,2, Rydell G.E. 3, Höök F. 1
Published in: Langmuir, 2017, Vol. 33 (16), p. 4049–4056
Multivalent receptor-mediated interactions between virions and a lipid membrane can be weakened using competitive nonpathogenic ligand binding. In particular, the subsequent binding [...]

Targeting Tumor-Associated Exosomes with Integrin-Binding Peptides

Publication year: 2017
Authors: Carney R.P. 1, Hazari S. 1, Rojalin T. 2,3, Knudson A. 1, Gao T. 3,4, Tang Y. 3,4, Liu R. 1, Viitala T. 5, Yliperttula M. 5,6, Lam K.S. 1,7
Published in: Advanced Biosystems, 2017, Vol. 1 (5), p. 1600038
All cells expel a variety of nanosized extracellular vesicles (EVs), including exosomes, with composition reflecting the cells' biological state. Cancer pathology is dramatically mediated by EV trafficking [...]