Combining MP-SPR and electrochemistry in material sciences

MP-SPR method can be used in conjunction with a variety of electrochemical techniques for gathering both optical and electrochemical real-time data simultaneously from the same reaction. Multiple electrochemical methods such as potentiometric, amperometric or impedance spectroscopy can be measured.

The potentiostat can be used for electrodeposition of thin films in-situ, to modify electrical potential across a surface to study biomimetic surfaces (electrochemical switching) or to gather information with a technology sensitive to other type of information than optical changes.

Five typical research areas to combine electrochemistry and MP-SPR:

  • Electroswithchable reactions and functional biomaterials
  • Real-time measurements of conformational changes
  • Development of simple electrochemical sensors in one device - more information here
  • Supported lipid membrane quality assessment - more information here
  • Catalytical bioreactions

See reasons to choose MP-SPR for switchable material development: 

  • Easy ex-situ modification of SPR surfaces
  • Simultaneous recording of electrochemical and MP-SPR signals
  • Compatible with most organic solvents
  • Conformational changes in real-time
  • No swelling artifacts

See five key questions in electroswitchable material development that MP-SPR can answer:

  • How fast does protein X adsorb onto surface A?
  • How does the reaction change at different temperature, pH and electric potential?
  • How fast is the electrodeposition?
  • How fast is the catalysis?
  • How much liquids can the material uptake and release at different pH?

See selected Application Notes to see that MP-SPR works:

  • AN#143 Real-time monitoring of antibody binding by parallel MP-SPR, potentiometry and impedance spectroscopy
  • AN#142 Real-time monitoring of metal stripping and deposition with EC-MP-SPR
  • AN#140 Self-assembly of gold nanoparticles measured with MP-SPR
  • AN#136 Polymer collapse due to pH or electric potential change monitored with MP-SPR

Selected publications:

Electroswitchable surfaces:

Electrochemical sensor development using MP-SPR:

What our users say about MP-SPR for development of biomimetic surfaces:

"We use MP-SPR to quantify conformation changes of proteins at the surface under different environmental conditions." 
Prof. Barbara Jachimska, Polish Academy of Sciences, Poland 


 


 

See five reasons to choose MP-SPR for electrochemical studies.