MP-SPR for biocompatibility studies

MP-SPR allows you to conduct a complete study of your material all the way from characterization, interaction with proteins, serum and plasma up to interaction with bacteria and cells.

 
 

See reasons to choose MP-SPR for biocompatibility studies:

  • From thin films up to micrometer-thick coatings!
  • Selection of suitable surface model and surface characterization
  • Interaction with specific proteins
  • Interaction of full serum and plasma
  • Interaction with live cells or bacteria

See key questions about biocompatibility that MP-SPR can answer:

  • How does protein attach to a polymer?
  • How does 100% serum interact with a material?
  • How does a cleaning process, material processing, temperature or ageing of the materials affect the material-blood interaction?
  • When does a material activate the complement system?
  • How does shear stress affect to the interaction kinetics?
  • What is the swelling dynamics of the material and how do the optical properties change?
  • Which surface modification results in the best barrier properties?
  • What is the adsorbed mass of blood component?
  • What is the minimum thickness of a coating to provide a specific biofunctionality?

See selected Application Notes to see that MP-SPR works:

  • AN#168 Biomolecule affinity and concentration studies in human serum
  • AN#160 Biosensor for bacteria detection from powdered milk
  • AN#163 Characterization of micrometer thick layers of spin-coated chitin
  • AN#154 Real- time cancer cell detection and cell adhesion on implant material's surface
  • AN#151 Drug delivery nanocarrier studies using MP-SPR 
  • AN#149 Polymer Characterization studies using MP-SPR - Adsorption studies and layer thickness

Selected publications: