BioNavis: Excellence in Surface Plasmon Resonance

SPR Navi™ instruments have been developed for surface analysis in a number of key application areas, expanding the use of SPR from biomolecular interactions to new applications such as material characterization and sensor development. 

 

MP-SPR: The new generation of SPR

SPR Navi™ represents a generation shift in surface plasmon resonance (SPR) technology. The new Multi-Parametric SPR solves some of the previously open-ended questions and enables measurements on a number of samples, surfaces and conditions, traditional SPR cannot.

SPR Navi™: The only MP-SPR instruments on the market!

  • Real-time molecular interactions (kinetics, on-/off-rates, adsorption, desorption, affinity, concentration, adhesion
  • Physical properties (thickness, swelling, adsorbed mass) 
  • Optical properties (complex refractive index) 
  • Electrochemical behavior

on polymers, metals, alloys, ceramics, organic layers (incl. graphene, SiO2, TiO2, cell layers, Pt, Cu, cellulose, PET, PP, nanoparticles,..)
ranging from a few Ångströms to a few microns in thickness and
interacting with samples in gas and liquid environment.

Key Questions that SPR Navi™ can answer

Life Sciences

  • What is the affinity and on- and off-rates for molecule X interacting with protein Y?
  • How does this surface/analyte interaction change when the electrical potential is changed? 

Material Science

  • How does this polyelectrolyte multilayer grow?
  • How thick is the monolayer and what is the refractive index?
  • What is the thickness and refractive index of the nanolayers in the nanolaminate?

Sensor Development

  • Is the biosensor that I have designed working better than the previous one?
  • How does the surface of my biosensor interact with sample X?

Testimonials

"It is essential for us to decouple the contribution of hydration and bound water for quantification of adsorbed mass, layer thickness, etc."

Prof. Orlando Rojas
NCSU, USA and Aalto University, Finland

"With MP-SPR, we are able to observe and quantify the differences in cell uptake and kinetics of nanoparticles in dependence with the surface characteristics of the nanoparticle and their targeting."

Academy Research Fellow,
Tapani Viitala
University of Helsinki, Finland 

"MP-SPR is flexible instrument that allows us to connect the power of traditional separation techniques, such as LC, with the quantification of interactions by SPR."

Dr. Jeroen Kool
VU Amsterdam, The Netherlands 

"We use MP-SPR to quantify conformation changes of proteins at the surface under different environmental conditions."

Prof. Barbara Jachimska
Polish Academy of Sciences, Poland 

"We appreciate the versatility of the MP-SPR and the great technical support. Our multi-disciplinary research stretches from DNA-technology to stimulus-responsive polymers, and the MP-SPR has become a reliable and appreciated key instrument in our daily work."

Prof. Thomas Schäfer
Polymat UPV/EHU, Spain

Specifications

  • SPR angle range: 40° - 78°
  • Refractive index (RI) range: 1.00 - 1.40+
  • Smalles detected molecule: 2 Da (hydrogen measured in gas)
  • Largest detected: cells, liposomes, nanoparticles
  • Sensitivity: picomolar real-time label-free, attomolar with a color dye
  • Fastest sampling rate: from 4 ms
  • Measurable layer thickness: 5 Å -100 nm and 300 nm to µms

Accessories and Consumables

  • Additional set of lasers enabling true RI and thickness measurements, work with cell monolayers and extending the working range
  • Flow cells: standard (PDMS), electrochemistry, high chemical resistance (PEEK), gas
  • Sensor slides: Au-coated, metallic, non-metallic, carboxymethyldextran, custom
  • Software for SPR Navi™

 

SPR Navi™? SPR Navi™!

NOTE OUR NEW ADDRESS!! Oy BioNavis Ltd, Elopellontie 3C, 334 70 Ylöjärvi, FINLAND +358 44 5872001, info(...@...)bionavis.com

LATEST NEWS

MEET US AT:

Event Date/Time
ISSCR 2015 Annual Meeting June 24, 2015 to June 27, 2015
BioNavis is going to participate in International Society for Stem Cell Research 2015 Annual Meeting (ISSCR) that takes place on June 24-27 in Stockholm, Sweden.  The ISSCR is the premier international society for stem cell science, an organization ...
EBSA 2015 July 18, 2015 to July 22, 2015
BioNavis is going to participate in 10th European Biophysics Congress (EBSA 2015) that takes place on July 18-22 in Dresden, Germany. Outstanding speakers from Europe and overseas as well as state-of-the-art satellite symposia, oral and poster pr...
CRS 42nd Annual Meeting & Exposition July 26, 2015 to July 29, 2015
BioNavis is going to participate in 42nd Annual Meeting & Exposition of the Controlled Release Society that takes place on July 26-29 in Edinburgh, Scotland. BioNavis regularly participates in CRS Annual Meetings, and this year is going to be special ...
1st ICASS Shanghai July 27, 2015 to July 30, 2015
BioNavis is going to participate in 1st International Conference on Applied Surface Sciences (ICASS) that takes place on 27-30 July 2015 in Shanghai, China. Conference Topics are: Surface science of catalysis, electrocatalysis and photocatalysis Surface...

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