BioNavis: Excellence in Surface Plasmon Resonance

SPR Navi™ instruments have been developed for surface analysis in a number of key application areas, expanding the use of SPR from biomolecular interactions to new applications such as material characterization and sensor development. 

 

MP-SPR: The new generation of SPR

SPR Navi™ represents a generation shift in surface plasmon resonance (SPR) technology. The new Multi-Parametric SPR solves some of the previously open-ended questions and enables measurements on a number of samples, surfaces and conditions, traditional SPR cannot.

SPR Navi™: The only MP-SPR instruments on the market!

  • Real-time molecular interactions (kinetics, on-/off-rates, adsorption, desorption, affinity, concentration, adhesion
  • Physical properties (thickness, swelling, adsorbed mass) 
  • Optical properties (complex refractive index) 
  • Electrochemical behavior

on polymers, metals, alloys, ceramics, organic layers (incl. graphene, SiO2, TiO2, cell layers, Pt, Cu, cellulose, PET, PP, nanoparticles,..)
ranging from a few Ångströms to a few microns in thickness and
interacting with samples in gas and liquid environment.

Key Questions that SPR Navi™ can answer

Life Sciences

  • What is the affinity and on- and off-rates for molecule X interacting with protein Y?
  • How does this surface/analyte interaction change when the electrical potential is changed? 

Material Science

  • How does this polyelectrolyte multilayer grow?
  • How thick is the monolayer and what is the refractive index?
  • What is the thickness and refractive index of the nanolayers in the nanolaminate?

Sensor Development

  • Is the biosensor that I have designed working better than the previous one?
  • How does the surface of my biosensor interact with sample X?

Testimonials

 

"BioNavis' SPR Navi system allows unique configurations for multiple concurrent research projects"

Prof. Orlando Rojas
North Carolina State University in Raleigh
United States

 

"We are optimizing the SPR Navi instrument to be used as a standard method in our drug discovery tools platform"

Prof. head of division, Marjo Yliperttula
Division of Biopharmaceutics and pharmacokinetics 
Faculty of Pharmacy, University of Helsinki, Finland

Specifications

  • SPR angle range: 40° - 78°
  • Refractive index (RI) range: 1.00 - 1.40+
  • Smalles detected molecule: 2 Da (hydrogen measured in gas)
  • Largest detected: cells, liposomes, nanoparticles
  • Sensitivity: picomolar real-time label-free, attomolar with a color dye
  • Fastest sampling rate: from 4 ms
  • Measurable layer thickness: 5 Å -100 nm and 300 nm to µms

Accessories and Consumables

  • Additional set of lasers enabling true RI and thickness measurements, work with cell monolayers and extending the working range
  • Flow cells: standard (PDMS), electrochemistry, high chemical resistance (PEEK), gas
  • Sensor slides: Au-coated, metallic, non-metallic, carboxymethyldextran, custom
  • Software for SPR Navi™

 

SPR Navi™? SPR Navi™!

NOTE OUR NEW ADDRESS!! Oy BioNavis Ltd, Elopellontie 3C, 334 70 Ylöjärvi, FINLAND +358 44 5872001, info(...@...)bionavis.com

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Event Date/Time
ESB 2014, UK August 31, 2014 to September 03, 2014
ESB 2014 31 August – 3 September 2014 in Liverpool, UK   BioNavis will participate in 26th Annual Conference of the European Society for Biomaterials (ESB). Welcome to visit us at booth no. 66 and hear more about MP-SPR technology.   http...

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